Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.57 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6445858 | 1.00 | NAAA (0.57) | NAAAEPHX1SMN1; SMN2HSD17B10HDAC8 | |
| SCHEMBL10001620 | 0.82 | NAAA (0.58) | NAAAEPHX1SMN1; SMN2HSD17B10CHRM1 | |
| SCHEMBL1341403 | 0.81 | NAAA (0.56) | NAAAEPHX1SMN1; SMN2HSD17B10HDAC8 | |
| SCHEMBL1341778 | 0.79 | SMN1; SMN2 (0.55) | NAAAEPHX1SMN1; SMN2HSD17B10HDAC8 | |
| SCHEMBL61528 | 0.78 | NAAA (0.61) | NAAAEPHX1SMN1; SMN2HSD17B10HDAC8 | |
| SCHEMBL19669659 | 0.78 | NAAA (0.61) | NAAAEPHX1SMN1; SMN2HSD17B10HDAC8 | |
| SCHEMBL7484827 | 0.78 | NAAA (0.61) | NAAAEPHX1SMN1; SMN2HSD17B10HDAC8 | |
| SCHEMBL1810307 | 0.76 | SMN1; SMN2 (0.61) | NAAAEPHX1SMN1; SMN2HSD17B10HDAC8 | |
| SCHEMBL2639022 | 0.76 | NAAA (0.86) | NAAAEPHX1SMN1; SMN2HSD17B10EPHX2 | |
| SCHEMBL6359440 | 0.76 | NAAA (0.86) | NAAAEPHX1SMN1; SMN2HSD17B10EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3191088-A1 | AN ANTICONVULSANT COMPOUND | Royal Holloway And Bedford New College (GB) | 2017-07-19 | — | — | EP | disclosed |
| WO-2016038379-A1 | AN ANTICONVULSANT COMPOUND | ROYAL HOLLOWAY AND BEDFORD NEW COLLEGE (GB) | 2016-03-17 | — | — | WO | disclosed |