Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.41 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.41 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.41 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | CDK4 | P11802 | 1/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.40 |
| ▸ | CCND1 | P24385 | 1/20 | 0.40 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.40 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8406054 | 0.83 | LCK (0.48) | KDM4EPTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL8406052 | 0.83 | LCK (0.48) | KDM4EPTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL1897191 | 0.82 | MGAM (0.45) | KDM4EGAAPTGER1PTGER4PTGER3 | |
| SCHEMBL1759270 | 0.79 | KDM4E (0.48) | KDM4EGAAPTGER1PTGER4PTGER3 | |
| SCHEMBL5507242 | 0.78 | NPC1 (0.59) | NPC1RAB9AMEN1KMT2AATM | |
| SCHEMBL1758846 | 0.78 | KDM1A (0.45) | KDM4EPTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL1638769 | 0.77 | PTGER1 (0.46) | NPC1RAB9AMAPTPTGER1PTGER4 | |
| SCHEMBL1897819 | 0.73 | MGAM (0.40) | KDM4EGAAPTGER1PTGER4PTGER3 | |
| SCHEMBL1759239 | 0.72 | NFE2L2 (0.49) | KDM4EGAAPTGER1PTGER4PTGER3 | |
| SCHEMBL1638665 | 0.72 | MAPT (0.39) | MAPTKDM4EGAAMAPK1PTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2493933-A2 | CATALYST COMPOUNDS AND USE THEREOF | ExxonMobil Chemical Patents Inc. (US) | 2012-09-05 | — | — | EP | disclosed |
| WO-2011056424-A2 | CATALYST COMPOUNDS AND USE THEREOF | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2011-05-12 | — | — | WO | disclosed |