Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14757118 | 1.00 | KDM4E (0.30) | KDM4E | |
| Hydrochloric Acid SCHEMBL14741362 | 0.99 | KDM4E (0.30) | KDM4E | |
| Hydrochloric Acid SCHEMBL14741360 | 0.99 | KDM4E (0.30) | KDM4E | |
| SCHEMBL14745344 | 0.88 | KIF11 (0.36) | KDM4E | |
| Hydrochloric Acid SCHEMBL18628145 | 0.86 | — | — | |
| SCHEMBL14757030 | 0.85 | — | — | |
| SCHEMBL14741509 | 0.84 | PTGS1 (0.32) | — | |
| SCHEMBL14741511 | 0.84 | PTGS1 (0.32) | — | |
| SCHEMBL18652993 | 0.84 | PTGS1 (0.32) | — | |
| SCHEMBL17593209 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016039938-A1 | POLYCYCLIC 2-PYRIDINONE ANTIBACTERIAL COMPOUNDS | PTC THERAPEUTICS, INC. (US) | 2016-03-17 | — | — | WO | disclosed |