Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.56 |
| ▸ | FFAR2 | O15552 | 2/20 | 0.36 |
| ▸ | SLC6A15 | Q9H2J7 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | XIAP | P98170 | 1/20 | 0.34 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.34 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.33 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Valine SCHEMBL1389041 | 0.83 | SLC7A5 (0.58) | SLC7A5LMNADPP8DPP9SLC1A3 | |
| Valine SCHEMBL1842424 | 0.83 | TDP1 (0.52) | SLC7A5FFAR2LMNASMN1; SMN2XIAP | |
| Valine SCHEMBL598198 | 0.82 | SLC7A5 (0.47) | SLC7A5LMNASMN1; SMN2XIAPBIRC2 | |
| Valine SCHEMBL27817390 | 0.80 | SLC7A5 (0.79) | SLC7A5LMNADPP8DPP9SLC1A3 | |
| Valine SCHEMBL28052598 | 0.79 | SLC7A5 (0.88) | SLC7A5LMNADPP8DPP9SLC1A3 | |
| Valine SCHEMBL4582565 | 0.79 | SLC7A5 (0.88) | SLC7A5LMNADPP8DPP9SLC1A3 | |
| Valine SCHEMBL14994137 | 0.79 | SLC7A5 (0.52) | SLC7A5LMNASLC1A3SLC1A2MEN1 | |
| Valine SCHEMBL2205229 | 0.77 | SLC7A5 (0.50) | SLC7A5LMNASMN1; SMN2DPP8DPP9 | |
| Valine SCHEMBL9359776 | 0.77 | SLC7A5 (0.50) | SLC7A5LMNASMN1; SMN2SLC1A3SLC1A2 | |
| Valine SCHEMBL7070552 | 0.76 | SLC7A5 (0.54) | SLC7A5LMNASLC1A3SLC1A2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011058478-A1 | SUBSTITUTED TRIAZOLOPYRIMIDINES AS PDE8 INHIBITORS | PFIZER INC. (US) | 2011-05-19 | — | — | WO | disclosed |
| EP-0125650-B1 | REACTIVE DYES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THE DYEING AND PRINTING OF SUBSTRATES | BAYER AG (DE) | 1987-04-01 | — | — | EP | disclosed |
| EP-0125650-A2 | Reactive dyes, process for their preparation and their use in the dyeing and printing of substrates | BAYER AG (DE) | 1984-11-21 | — | — | EP | disclosed |