Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | KMO | O15229 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SLC1A3 | P43003 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Valine SCHEMBL1759337 | 0.76 | SLC7A5 (0.56) | SLC7A5LMNAMEN1KMT2AKDM4C | |
| Valine SCHEMBL28760345 | 0.74 | SLC7A5 (0.71) | SLC7A5LMNANR1I2PTGS1ADRA1A | |
| Valine SCHEMBL27817390 | 0.74 | SLC7A5 (0.79) | SLC7A5LMNANR1I2PTGS1ADRA1A | |
| Valine SCHEMBL27571970 | 0.73 | SLC7A5 (0.88) | SLC7A5LMNAPTGS1ALDH1A1SLC1A3 | |
| Valine SCHEMBL28052598 | 0.73 | SLC7A5 (0.88) | SLC7A5LMNANR1I2PTGS1ADRA1A | |
| Valine SCHEMBL2540234 | 0.73 | SLC7A5 (0.88) | SLC7A5LMNANR1I2PTGS1ADRA1A | |
| Valine SCHEMBL15602719 | 0.73 | SLC7A5 (0.88) | SLC7A5LMNAPTGS1ALDH1A1SLC1A3 | |
| Valine SCHEMBL4582565 | 0.73 | SLC7A5 (0.88) | SLC7A5LMNANR1I2PTGS1ADRA1A | |
| Valine SCHEMBL482773 | 0.73 | SLC7A5 (0.88) | SLC7A5LMNAPTGS1ALDH1A1SLC1A3 | |
| Valine SCHEMBL1813972 | 0.73 | SLC7A5 (1.00) | SLC7A5PTGS1ALDH1A1SLC1A3SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0816344-B1 | Process for the production of 2,5-diamino-4,6-dichloropyrimidine | LONZA AG (CH) | 2003-06-18 | — | — | EP | disclosed |
| EP-0816344-A1 | Process for the production of 2,5-diamino-4,6-dichloropyrimidine | LONZA AG (CH) | 1998-01-07 | — | — | EP | disclosed |