Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 10/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | GRM8 | O00222 | 1/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.33 |
| ▸ | ITGAV | P06756 | 2/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17597642 | 0.89 | PDE4D (0.38) | TBXAS1PDE4DLMNAGRM8GRM4 | |
| SCHEMBL17592613 | 0.81 | SYK (0.36) | PDE4DLMNAALDH1A1HTT | |
| SCHEMBL17592179 | 0.80 | PIM1 (0.46) | TBXAS1EPHX2TBXA2RGRM8GRM4 | |
| SCHEMBL17596793 | 0.80 | GAA (0.34) | TBXAS1PDE4DLMNAITGB3ITGAV | |
| SCHEMBL17595100 | 0.80 | SYK (0.33) | PDE4DLMNA | |
| SCHEMBL17592271 | 0.78 | SLC6A2 (0.35) | — | |
| SCHEMBL17099592 | 0.75 | MEN1 (0.35) | LMNAALDH1A1 | |
| SCHEMBL17591702 | 0.72 | TBXAS1 (0.48) | TBXAS1EPHX2LMNATBXA2RGRM8 | |
| SCHEMBL17596760 | 0.71 | TBXAS1 (0.60) | TBXAS1EPHX2PDE4DLMNAGRM8 | |
| SCHEMBL17593977 | 0.70 | TBXAS1 (0.48) | TBXAS1EPHX2PDE4DTBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016040188-A1 | 3-(3H-IMIDAZO[4,5-C]PYRIDIN-2-YL)-1H-PYRAZOLO[3,4-C]PYRIDINE AND THERAPEUTIC USES THEREOF | SAMUMED, LLC (US) | 2016-03-17 | — | — | WO | claimed |
| WO-2016040180-A1 | 3-(1H-BENZO[D]IMIDAZOL-2-YL)-1H-PYRAZOLO[3,4-C]PYRIDINE AND THERAPEUTIC USES THEREOF | SAMUMED, LLC (US) | 2016-03-17 | — | — | WO | claimed |