Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGALS3 | P17931 | 19/20 | 0.71 |
| ▸ | LGALS1 | P09382 | 10/20 | 0.62 |
| ▸ | MDM4 | O15151 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.53 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12549927 | 1.00 | LGALS3 (0.71) | LGALS3LGALS1MDM4TP53MDM2 | |
| SCHEMBL15806284 | 1.00 | LGALS3 (0.71) | LGALS3LGALS1MDM4TP53MDM2 | |
| SCHEMBL12572815 | 1.00 | LGALS3 (0.71) | LGALS3LGALS1MDM4TP53MDM2 | |
| SCHEMBL12550148 | 0.87 | LGALS3 (0.55) | LGALS3LGALS1LGALS8 | |
| SCHEMBL12572816 | 0.86 | LGALS3 (0.55) | LGALS3LGALS1LGALS8 | |
| SCHEMBL15806280 | 0.86 | LGALS3 (0.55) | LGALS3LGALS1LGALS8 | |
| SCHEMBL1955106 | 0.86 | LGALS3 (0.83) | LGALS3LGALS1LGALS8 | |
| SCHEMBL1955104 | 0.86 | LGALS3 (0.83) | LGALS3LGALS1LGALS8 | |
| SCHEMBL3284264 | 0.84 | LGALS3 (0.80) | LGALS3LGALS1LGALS8 | |
| SCHEMBL26964205 | 0.84 | LGALS3 (0.73) | LGALS3LGALS1LGALS8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2424873-A1 | NOVEL GALACTOSIDE INHIBITORS OF GALECTINS | Forskarpatent I SYD AB (SE) | 2012-03-07 | — | — | EP | disclosed |
| WO-2010126435-A1 | NOVEL GALACTOSIDE INHIBITORS OF GALECTINS | FORSKARPATENT I SYD AB (SE) | 2010-11-04 | — | — | WO | disclosed |