Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | BRAF | P15056 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2545006 | 0.81 | GAA (0.56) | ALDH1A1KDM4EMAPTSMN1; SMN2GAA | |
| SCHEMBL20427927 | 0.74 | PDE4D (0.71) | ALDH1A1KDM4EMAPTMAPK1PDE4D | |
| SCHEMBL4524302 | 0.73 | GAA (0.57) | ALDH1A1KDM4EMAPTPOLBSMN1; SMN2 | |
| SCHEMBL20427928 | 0.73 | CYP1A2 (0.60) | ALDH1A1KDM4EMAPTPOLBSMN1; SMN2 | |
| SCHEMBL1765721 | 0.72 | PDE4D (0.42) | ALDH1A1KDM4EPDE4DHPGDLMNA | |
| SCHEMBL14483300 | 0.72 | MEN1 (0.61) | ALDH1A1KDM4EMAPTPOLBSMN1; SMN2 | |
| SCHEMBL4506277 | 0.71 | LMNA (0.65) | ALDH1A1KDM4EMAPTGAAMAPK1 | |
| SCHEMBL17596364 | 0.71 | POLB (0.42) | ALDH1A1KDM4EMAPTPOLBSMN1; SMN2 | |
| SCHEMBL2559503 | 0.71 | PDE4D (0.56) | ALDH1A1KDM4EMAPTPOLBSMN1; SMN2 | |
| SCHEMBL12264899 | 0.70 | PDE4D (0.59) | ALDH1A1MAPTPOLBSMN1; SMN2PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016038143-A1 | MICROBIOCIDAL 4-(IMIDAZO[4,5-C]PYRIDIN-2-YL)-1,2,5-OXADIAZOL-3- AMINE COMPOUNDS HAVING AN OXIME GROUP IN POSITION 7 | SYNGENTA PARTICIPATIONS AG (CH) | 2016-03-17 | — | — | WO | disclosed |