Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT1 | P04628 | 12/20 | 0.49 |
| ▸ | TGFBR1 | P36897 | 10/20 | 0.49 |
| ▸ | CLK2 | P49760 | 9/20 | 0.46 |
| ▸ | CLK3 | P49761 | 9/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 9/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17587994 | 0.91 | WNT1 (0.53) | WNT1TGFBR1CLK2CLK3DYRK1A | |
| SCHEMBL17597503 | 0.89 | WNT1 (0.48) | WNT1TGFBR1CLK2CLK3DYRK1A | |
| SCHEMBL17588003 | 0.87 | WNT1 (0.53) | WNT1TGFBR1CLK2CLK3DYRK1A | |
| SCHEMBL17587995 | 0.86 | WNT1 (0.56) | WNT1TGFBR1CLK2CLK3DYRK1A | |
| SCHEMBL17587989 | 0.85 | WNT1 (0.54) | WNT1TGFBR1CLK2CLK3DYRK1A | |
| SCHEMBL17587999 | 0.85 | WNT1 (0.56) | WNT1TGFBR1CLK2CLK3DYRK1A | |
| SCHEMBL17587987 | 0.84 | CLK2 (0.56) | WNT1TGFBR1CLK2CLK3DYRK1A | |
| SCHEMBL17588005 | 0.83 | WNT1 (0.69) | WNT1TGFBR1CLK2CLK3DYRK1A | |
| SCHEMBL17588001 | 0.83 | WNT1 (0.67) | WNT1TGFBR1CLK2CLK3DYRK1A | |
| SCHEMBL17588004 | 0.83 | WNT1 (0.54) | WNT1TGFBR1CLK2CLK3DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016040182-A1 | 2-(1H-INDAZOL-3-YL)-1H-IMIDAZO[4,5-C]PYRIDINE AND THERAPEUTIC USES THEREOF | SAMUMED, LLC (US) | 2016-03-17 | — | — | WO | claimed |