SCHEMBL17597859

SCHEMBL17597859

Cc1cn([C@H]2CC[C@@H](COP(OCCC#N)N(C(C)C)C(C)C)O2)c(=O)[nH]c1=O

nearest known ligand 0.46

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ BCHE P06276 1/20 0.42
▸ TK1 P04183 7/20 0.38
▸ ALB P02768 1/20 0.35
▸ PKM P14618 1/20 0.35
▸ LMNA P02545 1/20 0.35
▸ BLM P54132 1/20 0.35
▸ PMP22 Q01453 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23061371 0.88 BCHE (0.34) BCHETK1ALBPKMLMNA
SCHEMBL8742416 0.85 POLB (0.51) BCHETK1
SCHEMBL4730531 0.85 TK1 (0.43) TK1
SCHEMBL20833548 0.85 BCHE (0.46) BCHETK1ALBPKMLMNA
SCHEMBL27364588 0.82 BCHE (0.48) BCHETK1ALBPKMLMNA
SCHEMBL16130881 0.82 TK1 (0.40) TK1
SCHEMBL20833438 0.82 TK1 (0.40) TK1ALBLMNABLM
SCHEMBL22335483 0.82 TK1 (0.36) TK1ALBPKMLMNABLM
SCHEMBL22335642 0.82 TK1 (0.36) TK1ALBPKMLMNABLM
SCHEMBL12462900 0.81 TK1 (0.40) TK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3137479-B1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF MAKING THE SAME GERON CORP (US) 2023-08-30 — — EP disclosed
EP-3922637-A1 MODIFIED OLIGONUCLEOTIDES FOR USE IN TREATMENT OF TAUOPATHIES Janssen Pharmaceutica NV (BE) 2021-12-15 — — EP disclosed
WO-2021198958-A1 NUCLEIC ACID POLYMERS Janssen Biopharma, Inc. (US) 2021-10-07 — — WO disclosed
EP-3191605-A1 A DROPLET-BASED METHOD AND APPARATUS FOR COMPOSITE SINGLE-CELL NUCLEIC ACID ANALYSIS The Broad Institute, Inc. (US) 2017-07-19 — — EP disclosed
WO-2016188868-A1 NUCLEOSIDE-LIPID COMPOUNDS WITH PH-SENSITIVE DIALKYLORTHOESTER CHAINS AND THEIR USE FOR TRANSPORTATION OR VECTORIZATION OF AT LEAST ONE THERAPEUTIC AGENT Universite de Bordeaux (FR) 2016-12-01 — — WO disclosed
WO-2016040476-A1 A DROPLET-BASED METHOD AND APPARATUS FOR COMPOSITE SINGLE-CELL NUCLEIC ACID ANALYSIS THE BROAD INSTITUTE, INC. (US) 2016-03-17 — — WO disclosed
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