SCHEMBL175988

SCHEMBL175988

O=C1CCCNC1=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5806729 0.97
Hydrochloric Acid SCHEMBL29153088 0.97 OR51E2 (0.50)
SCHEMBL4662855 0.92
SCHEMBL6665501 0.87 CRBN (0.50)
SCHEMBL27981972 0.84 OR51E2 (0.39)
SCHEMBL4619038 0.83 OR51E2 (0.48)
2-Pyrrolidone SCHEMBL28082054 0.83 OR51E2 (0.68)
SCHEMBL116223 0.81
SCHEMBL4620260 0.81 OR51E2 (0.46)
SCHEMBL2637407 0.79 FKBP5 (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1733 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122080325-A Block copolymer, binder containing block copolymer, positive electrode slurry and solid-state battery 2026-05-26 CN claimed
WO-2023239629-A1 COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THAT DEGRADE CDK2 Plexium, Inc. (US) 2023-12-14 WO claimed
US-11666547-B2 Methods for treating cognitive deficits in a subject having schizophrenia, bipolar disorder, or psychiatric depression, and exhibiting cognitive deficits by administering an antagonist of the Na+-K+-2Cl-cation-chloride cotransporter isoform 1 (NKCC1) NORTHWESTERN UNIVERSITY (US) 2023-06-06 US claimed
CN-216440619-U Reation kettle is used in piperidine diketone preparation processing 山东轩鸿生物医药有限公司 2022-05-06 CN claimed
CN-109651334-B Process for preparing substituted piperidinedione derivatives 南京卡文迪许生物工程技术有限公司 2021-12-21 CN claimed
US-20200405672-A1 METHODS FOR TREATING PSYCHIATRIC DISEASES AND DISORDERS AND THE SYMPTOMS THEREOF IN A SUBJECT BY ADMINISTERING AN ANTAGONIST OF THE NA+-K+-2CL- CATION-CHLORIDE COTRANSPORTER ISOFORM 1 (NKCC1) NORTHWESTERN UNIVERSITY (US) 2020-12-31 US claimed
CN-111434659-A Pomalidomide prodrug salt 南京诺瑞特医药科技有限公司 2020-07-21 CN claimed
US-10716779-B2 Methods and compositions for treating foot or hand pain SANDERS JENNIFER L (US) 2020-07-21 US claimed
CN-111001437-A AEI/AFX structure symbiotic composite molecular sieve, preparation method and SCR application thereof 中触媒新材料股份有限公司 2020-04-14 CN claimed
CN-111001436-A Intergrowth composite molecular sieve with AEI/KFI structure, preparation method thereof and SCR application thereof 中触媒新材料股份有限公司 2020-04-14 CN claimed
US-4994475-A Treating anxiety with dioxopiperidines; bacterial and viral infections NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1991-02-19 US claimed
US-4918084-A ANXIOLYTIC AGENTS; BENZODIAZEPINE INVERSE AGONIST ANTAGONISTS NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1990-04-17 US claimed
US-4738973-A ANXIOLYTIC AGENTS NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1988-04-19 US claimed
US-4721710-A Derivatives of piperidinedione for protecting the myocardium presenting an anti-arrythmic activity, and pharmaceutical compositions SANOFI 1988-01-26 US claimed
EP-0129694-B1 DEEP ULTRA-VIOLET LITHOGRAPHIC RESIST COMPOSITION International Business Machines Corporation (US) 1987-11-11 EP claimed
EP-0216555-A2 Use of dioxopiperidine derivatives in the treatment of anxiety, for the reduction of chronic abnormally high brain levels of serotonin or 5-hydroxy-indoleacetic acid, and in the treatment of bacterial or viral infections BTG INTERNATIONAL LIMITED (GB) 1987-04-01 EP claimed
CN-86103071-A Antipsychotic fused-ring pyridylpiperazine derivatives 1987-03-18 CN claimed
CN-86100224-A The preparation method of psycholeptic 2-(4-butyl piperazine-1-yl) pyridines cyclic imide derivative 1986-11-19 CN claimed
EP-0110755-B1 PIPERIDINE DIONE DERIVATIVES WITH A MYOCARDIUM PROTECTING AND ANTIARRHYTMIC ACTIVITY, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THEM SANOFI S.A. (FR) 1986-10-01 EP claimed
EP-0110755-A1 Piperidine dione derivatives with a myocardium protecting and antiarrhytmic activity, process for their preparation and medicines containing them SANOFI S.A. (FR) 1984-06-13 EP claimed