Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 5/20 | 0.37 |
| ▸ | CDK5R1 | Q15078 | 5/20 | 0.37 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP12 | P39900 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 3/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.34 |
| ▸ | CDK2 | P24941 | 3/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.34 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7131234 | 0.85 | CYP3A4 (0.53) | HPRT1CYP3A4SLC29A1 | |
| SCHEMBL20012357 | 0.85 | CYP3A4 (0.53) | HPRT1CYP3A4SLC29A1 | |
| SCHEMBL20012093 | 0.81 | HPRT1 (0.45) | HPRT1CYP3A4SLC29A1HSP90AA1HSP90AB1 | |
| SCHEMBL19994279 | 0.81 | HPRT1 (0.45) | HPRT1CYP3A4SLC29A1HSP90AA1HSP90AB1 | |
| SCHEMBL19994282 | 0.81 | HPRT1 (0.45) | HPRT1CYP3A4SLC29A1HSP90AA1HSP90AB1 | |
| SCHEMBL17601915 | 0.80 | CYP3A4 (0.43) | HPRT1CYP3A4CDK5CDK5R1CDK1 | |
| SCHEMBL6664903 | 0.80 | FGFR1 (0.50) | HPRT1CYP3A4DHFRSLC29A1HSP90AA1 | |
| SCHEMBL2907738 | 0.79 | HSP90AA1 (0.37) | HPRT1CYP3A4DHFRSLC29A1MMP2 | |
| SCHEMBL385550 | 0.78 | CYP3A4 (0.45) | HPRT1CYP3A4CDK1CCNE1CDK2 | |
| SCHEMBL7128278 | 0.78 | CYP3A4 (0.52) | HPRT1CYP3A4SLC29A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2998307-B1 | PHOSPHORIC ACID/PHOSPHONIC ACID DERIVATIVES AND MEDICINAL USES THEREOF | BEIJING SL PHARMACEUTICAL CO LTD (CN) | 2018-10-31 | — | — | EP | disclosed |
| US-20160115186-A1 | PHOSPHORIC ACID/PHOSPHONIC ACID DERIVATIVES AND MEDICINAL USES THEREOF | Nanjing Cavendish Bio-Engineering Technology Co., Ltd. (CN) | 2016-04-28 | — | — | US | disclosed |
| EP-2998307-A1 | PHOSPHORIC ACID/PHOSPHONIC ACID DERIVATIVES AND MEDICINAL USES THEREOF | Beijing Meibeita Drug Res Co., Ltd (CN) | 2016-03-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160115186-A1 | PHOSPHORIC ACID/PHOSPHONIC ACID DERIVATIVES AND MEDICINAL USES THEREOF | P2RY1, SQLE, PHOSPHO1 | HPRT1 1072/4885CYP3A4 792/4885CDK5 917/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.