Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | BRAF | P15056 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | S100A4 | P26447 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.33 |
| ▸ | TUBB | P07437 | 1/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.33 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17599590 | 1.00 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDHDAC4HDAC2 | |
| SCHEMBL17599641 | 0.92 | KDM4E (0.48) | ALDH1A1KDM4EHPGDHDAC4HDAC2 | |
| SCHEMBL2593421 | 0.87 | KDM4E (0.36) | ALDH1A1KDM4EHPGDCNR1CNR2 | |
| SCHEMBL2591573 | 0.87 | ALDH1A1 (0.51) | ALDH1A1KDM4EHPGDHDAC4HDAC2 | |
| SCHEMBL17599591 | 0.83 | KDM4E (0.47) | ALDH1A1KDM4EHPGDHDAC4HDAC2 | |
| SCHEMBL17599642 | 0.83 | KDM4E (0.47) | ALDH1A1KDM4EHPGDHDAC4HDAC2 | |
| SCHEMBL2592149 | 0.82 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDHDAC4HDAC2 | |
| SCHEMBL2588129 | 0.82 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDHDAC4HDAC2 | |
| SCHEMBL14736959 | 0.82 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDHDAC4HDAC2 | |
| SCHEMBL2592461 | 0.82 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDHDAC4HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2563770-B1 | BIARYL PHOSPHODIESTERASE INHIBITORS | LEO PHARMA AS (DK) | 2016-03-23 | — | — | EP | claimed |