Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 8/20 | 0.32 |
| ▸ | CA1 | P00915 | 7/20 | 0.32 |
| ▸ | CA4 | P22748 | 6/20 | 0.32 |
| ▸ | CA7 | P43166 | 6/20 | 0.32 |
| ▸ | CA9 | Q16790 | 4/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 5/20 | 0.32 |
| ▸ | CA5A | P35218 | 4/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.32 |
| ▸ | PPARG | P37231 | 3/20 | 0.32 |
| ▸ | PPARD | Q03181 | 3/20 | 0.32 |
| ▸ | PPARA | Q07869 | 2/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2584463 | 0.89 | KDM4E (0.48) | KDM4EALDH1A1HPGDLMNASMN1; SMN2 | |
| SCHEMBL2592780 | 0.87 | KDM4E (0.50) | KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL2591462 | 0.85 | KDM4E (0.48) | KDM4EALDH1A1HPGDLMNASMN1; SMN2 | |
| SCHEMBL2592881 | 0.84 | ALDH1A1 (0.50) | KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL2592309 | 0.81 | KDM4E (0.49) | KDM4EALDH1A1HPGDSMN1; SMN2ALOX5AP | |
| SCHEMBL7713098 | 0.79 | ALDH1A1 (0.49) | KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL2584646 | 0.79 | KDM4E (0.41) | KDM4EALDH1A1HPGDLMNASMN1; SMN2 | |
| SCHEMBL2587525 | 0.79 | ALDH1A1 (0.46) | KDM4EALDH1A1HPGDSMN1; SMN2MAOB | |
| SCHEMBL2593543 | 0.78 | ALDH1A1 (0.50) | KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL2590142 | 0.78 | KDM4E (0.41) | KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2563770-B1 | BIARYL PHOSPHODIESTERASE INHIBITORS | LEO PHARMA AS (DK) | 2016-03-23 | — | — | EP | claimed |