SCHEMBL176039

SCHEMBL176039

c1ccc(-c2nccnc2-c2ccccn2)nc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.68
LMNA P02545 3/20 0.68
CCR1 P32246 3/20 0.68
CCR5 P51681 3/20 0.68
CCR8 P51685 3/20 0.68
CYP1A2 P05177 1/20 0.68
POLB P06746 1/20 0.68
METAP1 P53582 1/20 0.68
BLM P54132 1/20 0.68
HIF1A Q16665 1/20 0.68
DOHH Q9BU89 1/20 0.68
P4HTM Q9NXG6 1/20 0.68
NPC1 O15118 6/20 0.56
TP53 P04637 4/20 0.56
RAB9A P51151 4/20 0.56
ALOX15 P16050 3/20 0.56
SMN1; SMN2 Q16637 3/20 0.56
L3MBTL1 Q9Y468 3/20 0.56
TDP1 Q9NUW8 2/20 0.56
HTT P42858 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29350626 0.91 KDM4E (0.56) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL30482884 0.85 KDM4E (0.93) KDM4ELMNACCR1CCR5CCR8
SCHEMBL14380272 0.84 KDM4E (0.62) KDM4ELMNACCR1CCR5CCR8
SCHEMBL8894024 0.84 KDM4E (0.54) KDM4ELMNACCR1CCR5CCR8
SCHEMBL323086 0.83 KDM4E (0.68) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL29907716 0.82 KDM4E (1.00) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL29351528 0.82 KDM4E (1.00) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL5922 0.82 KDM4E (1.00) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL3711450 0.82 KDM4E (1.00) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL6795069 0.79 KDM4E (0.93) KDM4ELMNACCR1CCR5CCR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 302 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119081361-A Preparation of rare earth light conversion film and agricultural application thereof 广西江和农业科技有限公司 2024-12-06 CN claimed
CN-115449860-B Nickel-gold electroplating liquid for ceramic substrate and electroplating process thereof 深圳创智芯联科技股份有限公司 2024-08-20 CN claimed
CN-117843661-A Preparation, structure and fluorescence application of two mononuclear zinc complexes 桂林理工大学 2024-04-09 CN claimed
CN-115449860-A Nickel-gold electroplating solution for ceramic substrate and electroplating process thereof 深圳市创智成功科技有限公司 2022-12-09 CN claimed
CN-105483779-A Au-Sn alloy electroplating solution and electroplating method thereof SHENZHEN RUN SUN CHEMICAL TECH CO LTD 2016-04-13 CN claimed
US-8445475-B2 Supramolecular complexes as photoactivated DNA cleavage agents VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) 2013-05-21 US claimed
US-8395003-B2 Metal nanoparticle-based catalytic composition that contains a nitrogen-containing ligand in an ionic liquid, process for preparation, process for hydrogenation of an olefinic feedstock IFP Energies Nouvelles (FR) 2013-03-12 US claimed
US-8148360-B2 Comprising at least one metal to ligand charge transfer (MLCT) light absorbing metal, at least one bridging ligand, and at least one platinum based DNA binding unit; complexes bind to DNA through platinum site then photocleave DNA; use in controlling hyperproliferating cells VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) 2012-04-03 US claimed
US-7923185-B2 Pyrazine containing charge transport layer photoconductors XEROX CORPORATION (US) 2011-04-12 US claimed
US-20110033883-A1 IMAGING DYES AND USE THEREOF ROYAL COLLEGE OF SURGEONS IRELAND (IE) 2011-02-10 US claimed
US-6271400-B2 SILICON BASED ANHYDROUS OXIDANT; LIGAND; CATALYTIC ORGANO OR INORGANO RHENIUM OXIDE; CONTROLLING EXCESS WATER CONCENTRATION AND MAXIMIZING MONOPEROXOCOMPLEX FORMATION. THE SCRIPPS RESEARCH INSTITUTE 2001-08-07 US claimed
US-20010001798-A1 EPOXIDATION OF OLEFINS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2001-05-24 US claimed
US-5939568-A Accelerated catalysis of olefinic epoxidations THE SCRIPPS RESEARCH INSTITUTE (US) 1999-08-17 US claimed
WO-1998033786-A9 ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS 1998-12-30 WO claimed
US-5780459-A SALICYLIC ACID WITH ADDITIONAL ACTIVE MATERIALS THE PROCTER & GAMBLE COMPANY (US) 1998-07-14 US claimed
EP-0619386-B1 Electroplating of palladium or palladium alloys ATOTECH DEUTSCHLAND GMBH (DE) 1998-06-17 EP claimed
US-5487884-A CYTOPROTECTIVE AGENTS BY RADIATION RESISTANCE TO PREVENT SKIN CANCER AND PREMATURE AGING THE PROCTER & GAMBLE COMPANY (US) 1996-01-30 US claimed
EP-0619386-A1 Electroplating of palladium alloys ATOTECH Deutschland GmbH (DE) 1994-10-12 EP claimed
EP-0313305-A2 Photoprotection compositions comprising chelating agents THE PROCTER & GAMBLE COMPANY (US) 1989-04-26 EP claimed
US-4605677-A RUTHENIUM COMPOUND, COBALT COMPOUND, QUATERNARY PHOSPHONIUM COMPOUND AND N-HETEROCYCLE CATALYST SYSTEM TEXACO INC. (US) 1986-08-12 US claimed