SCHEMBL323086

SCHEMBL323086

c1ccc(-c2nc(-c3ccccn3)c(-c3ccccn3)nc2-c2ccccn2)nc1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 10/20 0.68
LMNA P02545 3/20 0.68
CCR1 P32246 3/20 0.68
CCR5 P51681 3/20 0.68
CCR8 P51685 3/20 0.68
CYP1A2 P05177 2/20 0.68
POLB P06746 1/20 0.68
METAP1 P53582 1/20 0.68
BLM P54132 1/20 0.68
HIF1A Q16665 1/20 0.68
DOHH Q9BU89 1/20 0.68
P4HTM Q9NXG6 1/20 0.68
NPC1 O15118 8/20 0.65
TP53 P04637 5/20 0.64
SMN1; SMN2 Q16637 5/20 0.64
ALOX15 P16050 4/20 0.64
L3MBTL1 Q9Y468 4/20 0.64
TDP1 Q9NUW8 3/20 0.64
HTT P42858 2/20 0.64
ALPL P05186 2/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14067720 0.89 KDM4E (0.55) KDM4ELMNACCR1CCR5CCR8
SCHEMBL13910995 0.87 KDM4E (0.59) KDM4ELMNACCR1CCR5CCR8
SCHEMBL2061612 0.87 KDM4E (0.70) KDM4ELMNACCR1CCR5CCR8
SCHEMBL7965339 0.85 KDM4E (0.81) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL722577 0.85 KDM4E (0.93) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL721272 0.85 KDM4E (0.93) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL29467582 0.85 KDM4E (0.93) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL3796795 0.85 KDM4E (0.93) KDM4ELMNACCR1CCR5CCR8
SCHEMBL22761528 0.84 KDM4E (0.55) KDM4ELMNACCR1CCR5CCR8
SCHEMBL176039 0.83 KDM4E (0.68) KDM4ELMNACCR1CCR5CCR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 206 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119081361-A Preparation of rare earth light conversion film and agricultural application thereof 广西江和农业科技有限公司 2024-12-06 CN claimed
CN-116606639-A Organic room temperature phosphorescent material with controllable afterglow performance and preparation method and application thereof 中国科学院宁波材料技术与工程研究所 2023-08-18 CN claimed
CN-112625068-B Preparation, structure and fluorescence of heterobinuclear nickel-europium complex 桂林理工大学 2022-09-30 CN claimed
US-8445475-B2 Supramolecular complexes as photoactivated DNA cleavage agents VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) 2013-05-21 US claimed
US-8395003-B2 Metal nanoparticle-based catalytic composition that contains a nitrogen-containing ligand in an ionic liquid, process for preparation, process for hydrogenation of an olefinic feedstock IFP Energies Nouvelles (FR) 2013-03-12 US claimed
US-8148360-B2 Comprising at least one metal to ligand charge transfer (MLCT) light absorbing metal, at least one bridging ligand, and at least one platinum based DNA binding unit; complexes bind to DNA through platinum site then photocleave DNA; use in controlling hyperproliferating cells VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) 2012-04-03 US claimed
US-20100228064-A1 PROCESS FOR HYDROGENATION OF AN AROMATIC FEEDSTOCK THAT AS CATALYST USES A SUSPENSION OF METAL NANOPARTICLES CONTAINING A NITROGEN-CONTAINING LIGAND IN AN IONIC LIQUID IFP (FR) 2010-09-09 US claimed
US-20100191027-A1 METAL NANOPARTICLE-BASED CATALYTIC COMPOSITION THAT CONTAINS A NITROGEN-CONTAINING LIGAND IN AN IONIC LIQUID, PROCESS FOR PREPARATION, PROCESS FOR HYDROGENATION OF AN OLEFINIC FEEDSTOCK IFP (FR) 2010-07-29 US claimed
US-20100047910-A1 SUPRAMOLECULAR COMPLEXES AS PHOTOACTIVATED DNA CLEAVAGE AGENTS VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) 2010-02-25 US claimed
US-20090061336-A1 LIGHT STABILIZER CONTAINING PHOTOCONDUCTORS XEROX CORPORATION (US) 2009-03-05 US claimed
EP-1718590-A1 CATALYST SYSTEM FOR AEOROBIC OXIDATION OF PRIMARY AND SECONDARY ALCOHOLS. The NutraSweet Company (US) 2006-11-08 EP claimed
US-20050272713-A1 Supramolecular complexes as photoactivated DNA cleavage agents VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. 2005-12-08 US claimed
US-6962910-B2 ((2,2'-bipyridine)2Os(2,3-bis(2-pyridyl)pyrazine)RhCl2(2,3-bis(2 -pyridyl) pyrazine) Os(2,2'-bipyridine)2)(X)5, where X is a counterion selected from PF6-, CL-, BR-, CF3SO3- and BF4- a supramolecular metal complex; photodynamic therapy VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) 2005-11-08 US claimed
WO-2005082825-A1 CATALYST SYSTEM FOR AEOROBIC OXIDATION OF PRIMARY AND SECONDARY ALCOHOLS. THE NUTRASWEET COMPANY (US) 2005-09-09 WO claimed
US-20030180767-A1 Supramolecular complexes as photoactivated DNA cleavage agents VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY 2003-09-25 US claimed
WO-2003002119-A1 TREATMENT AND PREVENTION OF LIPODERMATOSCLEROSIS JOHNSON & JOHNSON MEDICAL LIMITED (GB) 2003-01-09 WO claimed
US-5780459-A SALICYLIC ACID WITH ADDITIONAL ACTIVE MATERIALS THE PROCTER & GAMBLE COMPANY (US) 1998-07-14 US claimed
US-5487884-A CYTOPROTECTIVE AGENTS BY RADIATION RESISTANCE TO PREVENT SKIN CANCER AND PREMATURE AGING THE PROCTER & GAMBLE COMPANY (US) 1996-01-30 US claimed
US-5320969-A Measuring the change in color when complexing a metal compound and colored indicator in a buffered solution of biological sample, e.g. urine MILES INC. (US) 1994-06-14 US claimed
EP-0313305-A2 Photoprotection compositions comprising chelating agents THE PROCTER & GAMBLE COMPANY (US) 1989-04-26 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100228064-A1 PROCESS FOR HYDROGENATION OF AN AROMATIC FEEDSTOCK THAT AS CATALYST USES A SUSPENSION OF METAL NANOPARTICLES CONTAINING A NITROGEN-CONTAINING LIGAND IN AN IONIC LIQUID SET, NCL, TNK1 KDM4E 698/4885LMNA 2721/4885CCR1 3006/4885
US-20100191027-A1 METAL NANOPARTICLE-BASED CATALYTIC COMPOSITION THAT CONTAINS A NITROGEN-CONTAINING LIGAND IN AN IONIC LIQUID, PROCESS FOR PREPARATION, PROCESS FOR HYDROGENATION OF AN OLEFINIC FEEDSTOCK NCL, C9, ARG1 KDM4E 2293/4885LMNA 2898/4885CCR1 887/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.