Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 17/20 | 0.78 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | KDR | P35968 | 2/20 | 0.48 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.48 |
| ▸ | MUSK | O15146 | 1/20 | 0.48 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.48 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.48 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.48 |
| ▸ | PAK3 | O75914 | 1/20 | 0.48 |
| ▸ | STK10 | O94804 | 1/20 | 0.48 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.48 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.48 |
| ▸ | LCK | P06239 | 1/20 | 0.48 |
| ▸ | CSF1R | P07333 | 1/20 | 0.48 |
| ▸ | YES1 | P07947 | 1/20 | 0.48 |
| ▸ | LYN | P07948 | 1/20 | 0.48 |
| ▸ | RET | P07949 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1759413 | 0.85 | FLT3 (0.82) | FLT3KDRBMPR1BMUSKEPHB6 | |
| SCHEMBL772950 | 0.80 | LMNA (0.66) | FLT3LMNARXFP1APP | |
| SCHEMBL1759412 | 0.79 | FLT3 (0.91) | FLT3KDRBMPR1BMUSKEPHB6 | |
| SCHEMBL73673 | 0.79 | FLT3 (0.80) | FLT3KDRBMPR1BMUSKEPHB6 | |
| SCHEMBL771889 | 0.76 | APP (0.83) | FLT3LMNARXFP1APP | |
| SCHEMBL11037810 | 0.74 | LMNA (0.62) | LMNARXFP1APP | |
| SCHEMBL11008475 | 0.73 | MAPT (0.63) | FLT3LMNARXFP1APP | |
| SCHEMBL20493642 | 0.73 | FLT3 (0.88) | FLT3KDRBMPR1BMUSKEPHB6 | |
| SCHEMBL11035096 | 0.73 | MAPT (0.60) | FLT3LMNARXFP1APP | |
| SCHEMBL772949 | 0.72 | APP (0.77) | FLT3LMNARXFP1APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011056764-A1 | ISOTOPICALLY ENRICHED OR FLUORINATED IMIDAZO[2,1-B][1,3]BENZOTHIAZOLES | AMBIT BIOSCIENCES CORP. (US) | 2011-05-12 | — | — | WO | disclosed |