Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | DGKA | P23743 | 1/20 | 0.38 |
| ▸ | PRKCA | P17252 | 1/20 | 0.36 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.36 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.36 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL439159 | 0.95 | LMNA (0.53) | LMNAMAPTMAPK1ALDH1A1DGKA | |
| SCHEMBL1512843 | 0.94 | LMNA (0.42) | LMNAMAPTMAPK1ALDH1A1CYP1A2 | |
| SCHEMBL809817 | 0.93 | LMNA (0.56) | LMNAMAPTMAPK1ALDH1A1DGKA | |
| SCHEMBL809894 | 0.93 | LMNA (0.56) | LMNAMAPTMAPK1ALDH1A1DGKA | |
| SCHEMBL5969842 | 0.92 | LMNA (0.59) | LMNAMAPTMAPK1ALDH1A1DGKA | |
| SCHEMBL6848790 | 0.92 | LMNA (0.59) | LMNAMAPTMAPK1ALDH1A1DGKA | |
| SCHEMBL10890703 | 0.92 | LMNA (0.59) | LMNAMAPTMAPK1ALDH1A1DGKA | |
| SCHEMBL439162 | 0.89 | LMNA (0.47) | LMNAMAPTMAPK1ALDH1A1CYP1A2 | |
| SCHEMBL17698431 | 0.88 | LMNA (0.50) | LMNAMAPTMAPK1ALDH1A1CYP1A2 | |
| SCHEMBL7719581 | 0.88 | LMNA (0.50) | LMNAMAPTMAPK1ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9073241-B2 | Injection molding process and compositions with improved sealing characteristics for mold-in-place gaskets | Henkel IP & Holding GmbH (DE) | 2015-07-07 | — | — | US | disclosed |
| EP-2300535-B1 | COMPOSITIONS WITH IMPROVED SEALING CHARACTERISTICS FOR MOLD-IN-PLACE GASKETS | HENKEL CORP (US) | 2013-04-03 | — | — | EP | disclosed |
| US-20130062818-A1 | INJECTION MOLDING PROCESS AND COMPOSITIONS WITH IMPROVED SEALING CHARACTERISTICS FOR MOLD-IN-PLACE GASKETS | HENKEL CORPORATION (US) | 2013-03-14 | — | — | US | disclosed |
| US-20110115132-A1 | MOLD ASSEMBLY AND ATTENUATED LIGHT PROCESS FOR FABRICATING MOLDED PARTS | HENKEL CORPORATION (US) | 2011-05-19 | — | — | US | disclosed |
| WO-2010011835-A1 | MOLD ASSEMBLY AND ATTENUATED LIGHT PROCESS FOR FABRICATING MOLDED PARTS | HENKEL CORPORATION (US) | 2010-01-28 | — | — | WO | disclosed |