SCHEMBL1760600

SCHEMBL1760600

CCO[SiH](CCC1CC2C=CC1C2)OCC

nearest known ligand 0.41

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.41
ALDH1A1 P00352 2/20 0.41
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
HTT P42858 1/20 0.32
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28299964 0.90 KDM4E (0.40) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL4661360 0.84 KDM4E (0.40) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL3277483 0.83 KDM4E (0.44) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL6063036 0.83 KDM4E (0.40) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL24141597 0.77 KDM4E (0.45) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL19480321 0.77 KDM4E (0.43) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL6064230 0.74 KDM4E (0.40) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL109229 0.74 KDM4E (0.52) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL22264018 0.74 KDM4E (0.45) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL6064078 0.73 KDM4E (0.41) KDM4EALDH1A1MEN1KMT2AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110114925-A1 BUFFER BILAYERS FOR ELECTRONIC DEVICES HSU CHE-HSIUNG 2011-05-19 US claimed
EP-2232527-A1 BUFFER BILAYERS FOR ELECTRONIC DEVICES E. I. du Pont de Nemours and Company (US) 2010-09-29 EP claimed
WO-2009086337-A1 BUFFER BILAYERS FOR ELECTRONIC DEVICES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2009-07-09 WO claimed
US-20110114925-A1 BUFFER BILAYERS FOR ELECTRONIC DEVICES HSU CHE-HSIUNG 2011-05-19 US disclosed
EP-2232527-A1 BUFFER BILAYERS FOR ELECTRONIC DEVICES E. I. du Pont de Nemours and Company (US) 2010-09-29 EP disclosed
WO-2009086337-A1 BUFFER BILAYERS FOR ELECTRONIC DEVICES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2009-07-09 WO disclosed
US-7015292-B2 Silicon-containing olefin copolymer, crosslinkable rubber composition thereof, and use thereof MITSUI CHEMICALS, INC. (JP) 2006-03-21 US disclosed
US-20050038214-A1 Silicon-containing olefin copolymer, crosslinkable rubber composition thereof, and use thereof MITSUI CHEMICALS, INC. (JP) 2005-02-17 US disclosed