SCHEMBL28299964

SCHEMBL28299964

CCO[SiH](CCCC1CC2C=CC1C2)OCC

nearest known ligand 0.40

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.40
ALDH1A1 P00352 2/20 0.40
MEN1 O00255 1/20 0.31
HTT P42858 1/20 0.31
KMT2A Q03164 1/20 0.31
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1760600 0.90 KDM4E (0.41) KDM4EALDH1A1MEN1HTTKMT2A
SCHEMBL3277483 0.80 KDM4E (0.44) KDM4EALDH1A1MEN1HTTKMT2A
SCHEMBL4661360 0.78 KDM4E (0.40) KDM4EALDH1A1MEN1HTTKMT2A
SCHEMBL6064157 0.76 KDM4E (0.38) KDM4EALDH1A1
SCHEMBL11066677 0.76 KDM4E (0.49) KDM4EALDH1A1MEN1HTTKMT2A
SCHEMBL107841 0.76 KDM4E (0.49) KDM4EALDH1A1MEN1HTTKMT2A
SCHEMBL11071159 0.76 KDM4E (0.49) KDM4EALDH1A1MEN1HTTKMT2A
SCHEMBL1975023 0.75 KDM4E (0.46) KDM4EALDH1A1MEN1HTTKMT2A
SCHEMBL19689468 0.75 KDM4E (0.46) KDM4EALDH1A1MEN1HTTKMT2A
SCHEMBL6063573 0.75 KDM4E (0.40) KDM4EALDH1A1MEN1HTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109912735-B External electron donor for olefin polymerization catalyst, catalyst system and preparation method of polyolefin 中国科学院化学研究所 2020-09-29 CN claimed
CN-109912735-A The preparation method of olefin polymerization catalysis external electron donor, catalyst system and polyolefin 中国科学院化学研究所 2019-06-21 CN claimed
CN-109912735-B External electron donor for olefin polymerization catalyst, catalyst system and preparation method of polyolefin 中国科学院化学研究所 2020-09-29 CN disclosed
CN-109912735-A The preparation method of olefin polymerization catalysis external electron donor, catalyst system and polyolefin 中国科学院化学研究所 2019-06-21 CN disclosed