Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | PRKCI | P41743 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.39 |
| ▸ | THRB | P10828 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | RECQL | P46063 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31633427 | 0.84 | HMGCR (0.44) | HMGCRMAPK1HTTNPC1HPGD | |
| SCHEMBL4806602 | 0.84 | HMGCR (0.44) | HMGCRMAPK1HTTNPC1HPGD | |
| SCHEMBL1760544 | 0.83 | HTT (0.57) | MAPK1HTTNPC1HPGDRAB9A | |
| SCHEMBL31545962 | 0.83 | HMGCR (0.42) | HMGCRMAPK1HTTNPC1HPGD | |
| SCHEMBL5589047 | 0.83 | HMGCR (0.42) | HMGCRMAPK1HTTNPC1HPGD | |
| SCHEMBL10531604 | 0.80 | GSR (0.42) | HMGCRMAPK1HTTNPC1HPGD | |
| SCHEMBL10531617 | 0.80 | HMGCR (0.33) | HMGCRMAPK1HTTNPC1HPGD | |
| Formaldehyde SCHEMBL11068310 | 0.79 | PTPN1 (0.41) | HMGCRMAPK1HTTNPC1HPGD | |
| SCHEMBL27887691 | 0.77 | HMGCR (0.45) | HMGCRMAPK1HTTCNR1CNR2 | |
| SCHEMBL5676592 | 0.77 | PGAM1 (0.43) | HMGCRMAPK1HTTNPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2499676-A1 | SOLAR CELL MODULES WITH POLYMER ENCAPSULANT COMPRISING REDUCING AGENTS | E. I. du Pont de Nemours and Company (US) | 2012-09-19 | — | — | EP | disclosed |
| US-20110114159-A1 | SOLAR CELL MODULES WITH POLYMER ENCAPSULANT COMPRISING REDUCING AGENTS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-05-19 | — | — | US | disclosed |
| US-4571435-A | SUSTAINED RELEASE | TENNESSEE VALLEY AUTHORITY (US) | 1986-02-18 | — | — | US | disclosed |
| US-4379939-A | Preparation of nitrogen fertilizers from oxalate esters prepared by the oxidative carbonylation of alcohols over noble metal catalysts utilizing regenerable 2,5-cyclohexadiene-1,4-dione oxidants | TENNESSEE VALLEY AUTHORITY (US) | 1983-04-12 | — | — | US | disclosed |