SCHEMBL1760696

SCHEMBL1760696

C1CCOCC1.c1ccc2c(c1)Oc1ccccc1O2

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.50
LMNA P02545 4/20 0.50
CRHBP P24387 2/20 0.50
CRHR2 Q13324 2/20 0.50
MAOA P21397 2/20 0.50
MAOB P27338 2/20 0.50
HTT P42858 1/20 0.50
ITGB2 P05107 1/20 0.43
ICAM1 P05362 1/20 0.43
ITGAL P20701 1/20 0.43
ALDH1A1 P00352 1/20 0.42
AHR P35869 3/20 0.39
ALOX5 P09917 1/20 0.39
ABCG2 Q9UNQ0 1/20 0.38
GAA P10253 2/20 0.36
P2RX4 Q99571 1/20 0.36
NPSR1 Q6W5P4 1/20 0.34
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oxirane SCHEMBL27940104 0.83 SMN1; SMN2 (0.60) SMN1; SMN2LMNACRHBPCRHR2MAOA
Fluoride SCHEMBL28291124 0.80
SCHEMBL11505174 0.79 SMN1; SMN2 (0.71) SMN1; SMN2LMNACRHBPCRHR2MAOA
SCHEMBL15381227 0.78 LMNA (0.77) SMN1; SMN2LMNACRHBPCRHR2HTT
SCHEMBL3077321 0.78 SMN1; SMN2 (0.50) SMN1; SMN2LMNACRHBPCRHR2MAOA
SCHEMBL288378 0.77 LMNA (0.85) SMN1; SMN2LMNACRHBPCRHR2MAOA
SCHEMBL35802 0.77 LMNA (0.85) SMN1; SMN2LMNACRHBPCRHR2MAOA
SCHEMBL15301625 0.77 LMNA (0.85) SMN1; SMN2LMNACRHBPCRHR2MAOA
SCHEMBL1262733 0.77 LMNA (0.85) SMN1; SMN2LMNACRHBPCRHR2MAOA
SCHEMBL35680 0.77 LMNA (0.85) SMN1; SMN2LMNACRHBPCRHR2MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230045778-A9 HETEROGENEOUS HYDROGEN-CATALYST SOLID FUEL REACTION MIXTURE AND REACTOR BRILLIANT LIGHT POWER, INC. (US) 2023-02-09 US disclosed
US-20200299130-A1 HETEROGENEOUS HYDROGEN-CATALYST REACTOR BRILLIANT LIGHT POWER, INC. (US) 2020-09-24 US disclosed
US-20110114075-A1 HETEROGENEOUS HYDROGEN-CATALYST REACTOR BRILLIANT LIGHT POWER, INC. 2011-05-19 US disclosed
EP-2318307-A2 HETEROGENEOUS HYDROGEN-CATALYST REACTOR Blacklight Power, Inc. (US) 2011-05-11 EP disclosed
WO-2010014684-A2 HETEROGENEOUS HYDROGEN-CATALYST REACTOR BLACKLIGHT POWER, INC. (US) 2010-02-04 WO disclosed