Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VNN1 | O95497 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 2/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.41 |
| ▸ | PDE1C | Q14123 | 3/20 | 0.41 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.40 |
| ▸ | CCNC | P24863 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | CDK8 | P49336 | 1/20 | 0.40 |
| ▸ | PASK | Q96RG2 | 1/20 | 0.40 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.40 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.40 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17608697 | 0.87 | AR (0.43) | VNN1ARPTGER4PDE1CF2RL3 | |
| SCHEMBL17608644 | 0.83 | PTGER4 (0.51) | PTGER4F2RL3MEN1KMT2AGAA | |
| SCHEMBL30041675 | 0.77 | PDE1C (0.57) | VNN1ARPDE1CCCNCHTR2A | |
| SCHEMBL1144917 | 0.77 | PDE1C (0.57) | VNN1ARPDE1CCCNCHTR2A | |
| SCHEMBL16127813 | 0.77 | GAA (0.52) | PTGER4F2RL3MEN1KMT2AABHD6 | |
| SCHEMBL14977876 | 0.76 | F2RL3 (0.48) | PTGER4F2RL3MEN1KMT2ASLC16A3 | |
| SCHEMBL25413010 | 0.74 | MEN1 (0.52) | MAOAMAOBMEN1KMT2AGAA | |
| SCHEMBL25412355 | 0.73 | EHMT2 (0.51) | MAOAMAOB | |
| SCHEMBL15687040 | 0.73 | RECQL (0.54) | MEN1KMT2AABHD6GAARAB9A | |
| SCHEMBL30614183 | 0.73 | RECQL (0.54) | MEN1KMT2AABHD6GAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016041618-A1 | SUBSTITUTED INDAZOLES AND RELATED HETEROCYCLES | MERCK PATENT GMBH (DE) | 2016-03-24 | — | — | WO | disclosed |
| WO-2016041618-A1 | SUBSTITUTED INDAZOLES AND RELATED HETEROCYCLES | MERCK PATENT GMBH (DE) | 2016-03-24 | — | — | WO | disclosed |