Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 5/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 5/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 5/20 | 0.46 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17608449 | 0.84 | PTGER4 (0.51) | PTGER4MCL1F2RL3CYP1A2SMN1; SMN2 | |
| SCHEMBL17608479 | 0.83 | VNN1 (0.43) | PTGER4F2RL3MEN1KMT2AGAA | |
| SCHEMBL16127813 | 0.82 | GAA (0.52) | PTGER4F2RL3MEN1KMT2AGAA | |
| SCHEMBL14977876 | 0.81 | F2RL3 (0.48) | PTGER4F2RL3MEN1KMT2AGAA | |
| SCHEMBL24273650 | 0.77 | PTGER4 (0.61) | PTGER4MCL1DRD2TBXA2RCYP1A2 | |
| SCHEMBL29459644 | 0.77 | PTGER4 (0.61) | PTGER4MCL1DRD2TBXA2RCYP1A2 | |
| SCHEMBL1214836 | 0.77 | ELANE (0.64) | PTGER4MCL1GAAMAPTCYP1A2 | |
| SCHEMBL1897336 | 0.75 | PTGER4 (0.59) | PTGER4F2RL3CYP1A2SMN1; SMN2F2 | |
| SCHEMBL1553851 | 0.75 | SLC22A12 (0.58) | F2RL3MEN1KMT2AGAARAB9A | |
| SCHEMBL17608582 | 0.75 | F2RL3 (0.45) | PTGER4F2RL3MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016041618-A1 | SUBSTITUTED INDAZOLES AND RELATED HETEROCYCLES | MERCK PATENT GMBH (DE) | 2016-03-24 | — | — | WO | disclosed |
| WO-2016041618-A1 | SUBSTITUTED INDAZOLES AND RELATED HETEROCYCLES | MERCK PATENT GMBH (DE) | 2016-03-24 | — | — | WO | disclosed |