Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 17/20 | 0.77 |
| ▸ | CDK8 | P49336 | 17/20 | 0.77 |
| ▸ | CDK19 | Q9BWU1 | 2/20 | 0.77 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17608483 | 1.00 | CCNC (0.77) | CCNCCDK8CDK19GSK3BDYRK1A | |
| SCHEMBL17608747 | 1.00 | CCNC (0.77) | CCNCCDK8CDK19GSK3BDYRK1A | |
| SCHEMBL17608605 | 0.93 | CCNC (0.75) | CCNCCDK8CDK19GSK3BDYRK1A | |
| SCHEMBL17608647 | 0.87 | CCNC (0.75) | CCNCCDK8CDK19GSK3BDYRK1A | |
| SCHEMBL17608692 | 0.87 | CCNC (0.75) | CCNCCDK8CDK19GSK3BDYRK1A | |
| SCHEMBL17608649 | 0.86 | CCNC (0.78) | CCNCCDK8CDK19 | |
| SCHEMBL17608689 | 0.86 | CCNC (0.64) | CCNCCDK8CDK19GSK3BDYRK1A | |
| SCHEMBL17608512 | 0.86 | CCNC (0.75) | CCNCCDK8CDK19 | |
| SCHEMBL17608688 | 0.84 | CCNC (0.67) | CCNCCDK8CDK19KMT2A | |
| SCHEMBL17608674 | 0.84 | CCNC (0.67) | CCNCCDK8CDK19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016041618-A1 | SUBSTITUTED INDAZOLES AND RELATED HETEROCYCLES | MERCK PATENT GMBH (DE) | 2016-03-24 | — | — | WO | claimed |
| WO-2016041618-A1 | SUBSTITUTED INDAZOLES AND RELATED HETEROCYCLES | MERCK PATENT GMBH (DE) | 2016-03-24 | — | — | WO | disclosed |
| WO-2016041618-A1 | SUBSTITUTED INDAZOLES AND RELATED HETEROCYCLES | MERCK PATENT GMBH (DE) | 2016-03-24 | — | — | WO | disclosed |