Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 18/20 | 0.78 |
| ▸ | CDK8 | P49336 | 18/20 | 0.78 |
| ▸ | CDK19 | Q9BWU1 | 3/20 | 0.59 |
| ▸ | TTK | P33981 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17608605 | 0.91 | CCNC (0.75) | CCNCCDK8CDK19 | |
| SCHEMBL17608647 | 0.87 | CCNC (0.75) | CCNCCDK8CDK19PARP1 | |
| SCHEMBL17608692 | 0.86 | CCNC (0.75) | CCNCCDK8CDK19PARP1 | |
| SCHEMBL17608488 | 0.86 | CCNC (0.77) | CCNCCDK8CDK19 | |
| SCHEMBL17608483 | 0.86 | CCNC (0.77) | CCNCCDK8CDK19 | |
| SCHEMBL17608747 | 0.86 | CCNC (0.77) | CCNCCDK8CDK19 | |
| SCHEMBL17608689 | 0.85 | CCNC (0.64) | CCNCCDK8CDK19PARP1 | |
| SCHEMBL17608512 | 0.85 | CCNC (0.75) | CCNCCDK8CDK19PARP1 | |
| SCHEMBL17608227 | 0.85 | CCNC (0.76) | CCNCCDK8CDK19 | |
| SCHEMBL17608384 | 0.84 | CCNC (0.59) | CCNCCDK8CDK19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016041618-A1 | SUBSTITUTED INDAZOLES AND RELATED HETEROCYCLES | MERCK PATENT GMBH (DE) | 2016-03-24 | — | — | WO | claimed |
| WO-2016041618-A1 | SUBSTITUTED INDAZOLES AND RELATED HETEROCYCLES | MERCK PATENT GMBH (DE) | 2016-03-24 | — | — | WO | disclosed |