Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 2/20 | 0.49 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | HTR7 | P34969 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 6/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11255645 | 0.79 | GRIN2B (0.57) | GRIN2BHTR1AHTR2AHTR7DRD3 | |
| SCHEMBL17621231 | 0.76 | GRIN2B (0.45) | GRIN2BHTR1AHTR2AHTR7DRD3 | |
| SCHEMBL7344494 | 0.74 | GRIN2B (0.57) | GRIN2BHTR1AHTR2AHTR7DRD3 | |
| SCHEMBL5069516 | 0.74 | GRIN2B (0.50) | GRIN2BHTR1AHTR2AHTR7DRD3 | |
| Bromide SCHEMBL3843849 | 0.74 | GRIN2B (0.49) | GRIN2BHTR1AHTR2AHTR7DRD3 | |
| SCHEMBL8440778 | 0.73 | GRIN2B (0.53) | GRIN2BHTR1AHTR2AHTR7DRD3 | |
| Hydrochloric Acid SCHEMBL7349822 | 0.73 | GRIN2B (0.55) | GRIN2BHTR1AHTR2AHTR7DRD3 | |
| Hydrochloric Acid SCHEMBL10838416 | 0.73 | GRIN2B (0.55) | GRIN2BHTR1AHTR2AHTR7DRD3 | |
| SCHEMBL8439771 | 0.71 | GRIN2B (0.52) | GRIN2BHTR1AHTR2AHTR7DRD3 | |
| SCHEMBL2641171 | 0.70 | CRBN (0.51) | GRIN2BHTR1AHTR2AHTR7DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016044771-A1 | HAT INHIBITORS AND METHODS FOR THEIR USE | ABBVIE INC. (US) | 2016-03-24 | — | — | WO | claimed |