Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2895572 | 0.83 | DGAT1 (0.33) | DGAT1 | |
| SCHEMBL14962148 | 0.80 | DGAT1 (0.34) | DGAT1 | |
| SCHEMBL16880990 | 0.78 | DGAT1 (0.37) | DGAT1 | |
| SCHEMBL18000647 | 0.77 | DGAT1 (0.35) | DGAT1 | |
| SCHEMBL2888209 | 0.77 | DGAT1 (0.33) | DGAT1 | |
| SCHEMBL5928297 | 0.76 | MEN1 (0.39) | DGAT1 | |
| SCHEMBL34468818 | 0.75 | DGAT1 (0.32) | DGAT1 | |
| SCHEMBL15556084 | 0.74 | MEN1 (0.35) | DGAT1 | |
| SCHEMBL21858254 | 0.74 | DGAT1 (0.34) | DGAT1 | |
| SCHEMBL3500693 | 0.73 | DGAT1 (0.38) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016044777-A1 | HAT INHIBITORS AND METHODS FOR THEIR USE | ABBVIE INC. (US) | 2016-03-24 | — | — | WO | disclosed |
| WO-2016044777-A1 | HAT INHIBITORS AND METHODS FOR THEIR USE | ABBVIE INC. (US) | 2016-03-24 | — | — | WO | disclosed |