Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | ACHE | P22303 | 6/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.31 |
| ▸ | RAD52 | P43351 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19179671 | 0.98 | TSHR (0.43) | TSHRACHEGAAALDH1A1CYP3A4 | |
| SCHEMBL13585188 | 0.85 | TSHR (0.41) | TSHRACHETDP1 | |
| SCHEMBL18712265 | 0.85 | TSHR (0.48) | TSHRACHEGAAALDH1A1CYP3A4 | |
| SCHEMBL28143768 | 0.79 | TSHR (0.62) | TSHRACHEALDH1A1RAD52NPSR1 | |
| SCHEMBL17612015 | 0.78 | MEN1 (0.42) | TSHRALDH1A1HTT | |
| SCHEMBL17612012 | 0.78 | MEN1 (0.42) | TSHRALDH1A1HTT | |
| SCHEMBL28066760 | 0.78 | ACHE (0.45) | TSHRACHEGAAALDH1A1CYP3A4 | |
| SCHEMBL17973526 | 0.77 | TSHR (0.50) | TSHRACHEALDH1A1CYP3A4POLB | |
| SCHEMBL8395128 | 0.77 | TSHR (0.44) | TSHRACHEGAAALDH1A1CYP3A4 | |
| SCHEMBL27490981 | 0.77 | TSHR (0.39) | TSHRACHEALDH1A1CYP3A4POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170218247-A1 | THERMOSETTING COMPOSITION FOR USE AS LOST CIRCULATION MATERIAL | DOW GLOBAL TECHNOLOGIES LLC (US) | 2017-08-03 | — | — | US | disclosed |
| WO-2016043979-A1 | THERMOSETTING COMPOSITION FOR USE AS LOST CIRCULATION MATERIAL | DOW GLOBAL TECHNOLOGIES LLC (US) | 2016-03-24 | — | — | WO | disclosed |