Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 4/20 | 0.45 |
| ▸ | PDE4A | P27815 | 6/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 6/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | RAPGEF3 | O95398 | 2/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.43 |
| ▸ | AHCY | P23526 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29674371 | 0.90 | STING1 (0.56) | STING1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL16271105 | 0.90 | STING1 (0.56) | STING1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL14946346 | 0.90 | STING1 (0.56) | STING1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL22983991 | 0.90 | STING1 (0.56) | STING1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL17889822 | 0.90 | PDE4A (0.56) | STING1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL23813544 | 0.90 | STING1 (0.56) | STING1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9964279 | 0.90 | STING1 (0.56) | STING1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6895355 | 0.90 | STING1 (0.56) | STING1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL1801703 | 0.90 | PDE4A (0.56) | STING1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL29792990 | 0.90 | PDE4A (0.56) | STING1PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9290533-B2 | β-L-2′-deoxy-nucleosides for the treatment of hepatitis B | NOVARTIS AG (CH) | 2016-03-22 | — | — | US | disclosed |