Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 1/20 | 0.53 |
| ▸ | HSPA5 | P11021 | 2/20 | 0.39 |
| ▸ | HSPA8 | P11142 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.38 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.38 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.38 |
| ▸ | GAPDH | P04406 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
| ▸ | STAT6 | P42226 | 1/20 | 0.38 |
| ▸ | PI4KA | P42356 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17612654 | 0.93 | ADK (0.53) | ADKHSPA5HSPA8RXFP1ADORA3 | |
| SCHEMBL17612655 | 0.93 | ADK (0.53) | ADKHSPA5HSPA8RXFP1ADORA3 | |
| SCHEMBL17612652 | 0.89 | ADK (0.65) | ADKHSPA5HSPA8RXFP1ADORA3 | |
| SCHEMBL17612669 | 0.89 | ADK (0.65) | ADKHSPA5HSPA8RXFP1ADORA3 | |
| SCHEMBL17612673 | 0.89 | ADK (0.65) | ADKHSPA5HSPA8RXFP1ADORA3 | |
| SCHEMBL23618698 | 0.85 | ADK (0.47) | ADKRXFP1ADORA3HIF1AADORA2A | |
| SCHEMBL4863668 | 0.81 | ADK (0.82) | ADKKMT2A | |
| SCHEMBL12870452 | 0.81 | ADK (0.82) | ADKKMT2A | |
| SCHEMBL12870457 | 0.81 | ADK (0.82) | ADKKMT2A | |
| SCHEMBL17612674 | 0.80 | ADK (0.52) | ADKHSPA5HSPA8RXFP1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9289398-B2 | Methods for the production of functional protein from DNA having a nonsense mutation and the treatment of disorders associated therewith | PTC THERAPEUTICS, INC. (US) | 2016-03-22 | — | — | US | disclosed |