Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 18/20 | 0.47 |
| ▸ | BCR | P11274 | 18/20 | 0.47 |
| ▸ | BRAF | P15056 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17612965 | 0.92 | ABL1 (0.46) | ABL1BCRBRAF | |
| SCHEMBL12465367 | 0.87 | ABL1 (0.46) | ABL1BCRBRAF | |
| SCHEMBL12465183 | 0.82 | ABL1 (0.51) | ABL1BCR | |
| SCHEMBL12465089 | 0.79 | BRAF (0.44) | ABL1BCRBRAF | |
| SCHEMBL12465368 | 0.79 | ABL1 (0.43) | ABL1BCRBRAF | |
| SCHEMBL12465328 | 0.79 | ABL1 (0.43) | ABL1BCRBRAF | |
| SCHEMBL12465243 | 0.78 | ABL1 (0.43) | ABL1BCRBRAF | |
| SCHEMBL17612902 | 0.78 | ABL1 (0.46) | ABL1BCRBRAF | |
| SCHEMBL17612966 | 0.76 | ABL1 (0.47) | ABL1BCRBRAF | |
| SCHEMBL12397202 | 0.76 | ABL1 (0.52) | ABL1BCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2173734-B1 | CHEMICAL COMPOUNDS | BOEHRINGER INGELHEIM INT (DE) | 2016-03-23 | — | — | EP | disclosed |