Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 16/20 | 0.56 |
| ▸ | BCR | P11274 | 16/20 | 0.56 |
| ▸ | GPR142 | Q7Z601 | 1/20 | 0.51 |
| ▸ | BRAF | P15056 | 1/20 | 0.45 |
| ▸ | DDR2 | Q16832 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17612908 | 0.88 | ABL1 (0.54) | ABL1BCRGPR142BRAFDDR2 | |
| SCHEMBL12398682 | 0.87 | GPR142 (0.52) | ABL1BCRGPR142BRAF | |
| SCHEMBL17612987 | 0.85 | DDR2 (0.52) | ABL1BCRGPR142BRAFDDR2 | |
| SCHEMBL17612870 | 0.83 | ABL1 (0.52) | ABL1BCRGPR142DDR2 | |
| SCHEMBL17612976 | 0.83 | ABL1 (0.60) | ABL1BCRGPR142BRAF | |
| SCHEMBL17612918 | 0.82 | ABL1 (0.59) | ABL1BCRGPR142BRAF | |
| SCHEMBL17612982 | 0.81 | ABL1 (0.56) | ABL1BCRGPR142BRAF | |
| SCHEMBL17612945 | 0.81 | ABL1 (0.58) | ABL1BCRGPR142BRAF | |
| SCHEMBL17612949 | 0.80 | ABL1 (0.55) | ABL1BCRGPR142BRAF | |
| SCHEMBL17612941 | 0.80 | BRAF (0.59) | ABL1BCRGPR142BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2173734-B1 | CHEMICAL COMPOUNDS | BOEHRINGER INGELHEIM INT (DE) | 2016-03-23 | — | — | EP | disclosed |