Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 17/20 | 0.57 |
| ▸ | BCR | P11274 | 17/20 | 0.57 |
| ▸ | BRAF | P15056 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17612902 | 0.89 | ABL1 (0.46) | ABL1BCRBRAF | |
| SCHEMBL12397431 | 0.89 | ABL1 (0.51) | ABL1BCRBRAF | |
| SCHEMBL17612966 | 0.86 | ABL1 (0.47) | ABL1BCRBRAF | |
| SCHEMBL17612988 | 0.86 | BRAF (0.46) | ABL1BCRBRAF | |
| SCHEMBL12397439 | 0.83 | ABL1 (0.55) | ABL1BCR | |
| SCHEMBL12396954 | 0.83 | BRAF (0.47) | ABL1BCRBRAF | |
| SCHEMBL12397437 | 0.82 | ABL1 (0.49) | ABL1BCRBRAF | |
| SCHEMBL12397016 | 0.82 | ABL1 (0.49) | ABL1BCRBRAF | |
| SCHEMBL12397024 | 0.82 | ABL1 (0.48) | ABL1BCRBRAF | |
| SCHEMBL12396847 | 0.81 | BRAF (0.53) | ABL1BCRBRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2173734-B1 | CHEMICAL COMPOUNDS | BOEHRINGER INGELHEIM INT (DE) | 2016-03-23 | — | — | EP | disclosed |