Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | HSD17B3 | P37058 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL27733248 | 0.98 | SMN1; SMN2 (0.55) | SMN1; SMN2MAPTL3MBTL1ATMHSD17B3 | |
| SCHEMBL8051337 | 0.87 | SMN1; SMN2 (0.70) | SMN1; SMN2MAPTL3MBTL1ATMHSD17B3 | |
| Ethyne SCHEMBL8050785 | 0.82 | SMN1; SMN2 (0.64) | SMN1; SMN2MAPTL3MBTL1ATMHSD17B3 | |
| SCHEMBL10389933 | 0.80 | SMN1; SMN2 (0.83) | SMN1; SMN2MAPTL3MBTL1ATMHSD17B3 | |
| SCHEMBL13460757 | 0.78 | KDM4E (0.41) | SMN1; SMN2MAPTL3MBTL1HSD17B3RAB9A | |
| SCHEMBL2644065 | 0.78 | SMN1; SMN2 (0.59) | SMN1; SMN2MAPTL3MBTL1ATMHSD17B3 | |
| SCHEMBL1146446 | 0.78 | SMN1; SMN2 (0.65) | SMN1; SMN2MAPTL3MBTL1ALDH1A1HPGD | |
| SCHEMBL20620593 | 0.78 | SMN1; SMN2 (0.59) | SMN1; SMN2MAPTL3MBTL1ATMHSD17B3 | |
| SCHEMBL12300577 | 0.78 | GSK3B (0.38) | SMN1; SMN2MAPTL3MBTL1HSD17B3RAB9A | |
| SCHEMBL507067 | 0.78 | GSK3B (0.64) | SMN1; SMN2MAPTL3MBTL1ATMRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023183405-A2 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2023-09-28 | — | — | WO | disclosed |
| US-20230295133-A1 | PROCESS FOR PREPARING A COMPOUND USEFUL TO TREAT MYCOSES | PULMOCIDE LIMITED (GB) | 2023-09-21 | — | — | US | disclosed |
| EP-2485591-B1 | IMINOTHIADIAZINE DIOXIDE COMPOUNDS AS BACE INHIBITORS, COMPOSITIONS, AND THEIR USE | MERCK SHARP & DOHME (US) | 2016-03-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230295133-A1 | PROCESS FOR PREPARING A COMPOUND USEFUL TO TREAT MYCOSES | DPM1, CYP51A1, ERG28 | SMN1; SMN2 3696/4885MAPT 2626/4885L3MBTL1 4796/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.