Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17613734 | 0.92 | THRA (0.31) | THRATHRB | |
| SCHEMBL17613723 | 0.89 | TSHR (0.32) | THRATHRB | |
| SCHEMBL17613756 | 0.81 | KDM4E (0.32) | — | |
| SCHEMBL17613779 | 0.79 | THRA (0.31) | THRATHRB | |
| SCHEMBL17613749 | 0.79 | CYP2D6 (0.36) | CHRM2CHRM1CHRM3 | |
| SCHEMBL12022706 | 0.79 | — | — | |
| SCHEMBL12022740 | 0.79 | — | — | |
| SCHEMBL17613737 | 0.78 | THRA (0.31) | THRATHRB | |
| SCHEMBL17613731 | 0.77 | THRA (0.31) | THRATHRBCHRM2CHRM1CHRM3 | |
| SCHEMBL17613594 | 0.73 | HRH4 (0.34) | THRATHRBCHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2346883-B1 | SELF DELIVERING BIO-LABILE PHOSPHATE PROTECTED PRO-OLIGOS FOR OLIGONUCLEOTIDE BASED THERAPEUTICS AND MEDIATING RNA INTERFERENCE | PETERSEN SCOTT G (US) | 2016-03-23 | — | — | EP | disclosed |