Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17613718 | 0.88 | — | — | |
| SCHEMBL2171182 | 0.82 | TSHR (0.40) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL12022672 | 0.74 | — | — | |
| SCHEMBL10018265 | 0.74 | TDP1 (0.43) | — | |
| SCHEMBL17613701 | 0.72 | — | — | |
| SCHEMBL15890590 | 0.71 | TSHR (0.46) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL997382 | 0.70 | MEN1 (0.48) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL888204 | 0.70 | MEN1 (0.48) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL13301154 | 0.70 | MEN1 (0.48) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL26381747 | 0.70 | MEN1 (0.48) | TSHRMAPK1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2346883-B1 | SELF DELIVERING BIO-LABILE PHOSPHATE PROTECTED PRO-OLIGOS FOR OLIGONUCLEOTIDE BASED THERAPEUTICS AND MEDIATING RNA INTERFERENCE | PETERSEN SCOTT G (US) | 2016-03-23 | — | — | EP | disclosed |