Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10018266 | 0.83 | TDP1 (0.40) | TDP1NOS3NOS1NOS2 | |
| SCHEMBL10819880 | 0.80 | TDP1 (0.44) | TDP1NOS3NOS1NOS2 | |
| SCHEMBL17617940 | 0.78 | TDP1 (0.43) | TDP1NOS3NOS1NOS2 | |
| SCHEMBL10018264 | 0.77 | TDP1 (0.46) | TDP1NOS3NOS1NOS2 | |
| SCHEMBL3864690 | 0.77 | TDP1 (0.50) | TDP1NOS3NOS1NOS2 | |
| SCHEMBL17613718 | 0.75 | — | — | |
| SCHEMBL17613635 | 0.74 | TSHR (0.34) | — | |
| SCHEMBL17694523 | 0.73 | TDP1 (0.46) | TDP1NOS3NOS1NOS2 | |
| SCHEMBL15615739 | 0.73 | TDP1 (0.46) | TDP1NOS3NOS1NOS2 | |
| SCHEMBL10819874 | 0.71 | TDP1 (0.44) | TDP1NOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120142763-A1 | NUCLEIC ACID DELIVERY COMPOSITIONS AND METHODS OF USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-06-07 | — | — | US | disclosed |
| US-20120142763-A1 | NUCLEIC ACID DELIVERY COMPOSITIONS AND METHODS OF USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142763-A1 | NUCLEIC ACID DELIVERY COMPOSITIONS AND METHODS OF USE THEREOF | NSUN3, NSUN2, DIS3 | TDP1 71/4885NOS3 3187/4885NOS1 4256/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.