Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.34 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17599430 | 0.72 | KMT2A (0.51) | ACP1KDM4EMEN1ALDH1A1GAA | |
| SCHEMBL6602218 | 0.66 | CYP1A2 (0.61) | ACP1KDM4EALDH1A1GAAHPGD | |
| SCHEMBL30576383 | 0.61 | CYP1A2 (0.48) | KDM4EALDH1A1GAAHPGDCYP1A2 | |
| SCHEMBL10883903 | 0.61 | CYP1A2 (0.48) | KDM4EALDH1A1GAAHPGDCYP1A2 | |
| SCHEMBL16218700 | 0.60 | CYP2A6 (0.41) | ACP1KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL16470341 | 0.59 | ALDH1A1 (0.43) | KDM4EMEN1ALDH1A1GAAMAPT | |
| SCHEMBL30902268 | 0.59 | CYP2A6 (0.44) | ACP1KDM4EMEN1ALDH1A1HPGD | |
| SCHEMBL7307773 | 0.59 | CYP2A6 (0.44) | ACP1KDM4EMEN1ALDH1A1GAA | |
| SCHEMBL31037117 | 0.59 | CYP2A6 (0.44) | ACP1KDM4EMEN1ALDH1A1HPGD | |
| SCHEMBL7033688 | 0.59 | CYP2A6 (0.44) | ACP1KDM4EMEN1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2998295-A1 | Aryl substituted naphthyl sulfonamide derivatives as keap-1 modulators for the treatment of diabetes, obesity, dyslipidemia and related disorders | SANOFI (FR) | 2016-03-23 | — | — | EP | disclosed |