Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 15/20 | 0.76 |
| ▸ | CTSB | P07858 | 8/20 | 0.76 |
| ▸ | CTSL | P07711 | 7/20 | 0.76 |
| ▸ | CTSF | Q9UBX1 | 6/20 | 0.76 |
| ▸ | CTSS | P25774 | 3/20 | 0.76 |
| ▸ | CTSV | O60911 | 1/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8117533 | 0.90 | CTSK (0.76) | CTSKCTSBCTSLCTSFCTSS | |
| SCHEMBL16020393 | 0.88 | CTSK (0.60) | CTSKCTSBCTSLCTSFCTSS | |
| SCHEMBL15977393 | 0.88 | CTSK (0.61) | CTSKCTSBCTSLCTSFCTSS | |
| Odanacatib SCHEMBL18540595 | 0.87 | CTSK (1.00) | CTSKCTSBCTSLCTSFCTSS | |
| SCHEMBL22733917 | 0.87 | CTSK (0.83) | CTSKCTSBCTSLCTSFCTSS | |
| SCHEMBL22733918 | 0.87 | CTSK (0.83) | CTSKCTSBCTSLCTSFCTSS | |
| Odanacatib SCHEMBL1496266 | 0.87 | CTSK (1.00) | CTSKCTSBCTSLCTSFCTSS | |
| Odanacatib SCHEMBL15827397 | 0.87 | CTSK (1.00) | CTSKCTSBCTSLCTSFCTSS | |
| SCHEMBL15894170 | 0.87 | CTSK (0.83) | CTSKCTSBCTSLCTSFCTSS | |
| Odanacatib SCHEMBL3479347 | 0.87 | CTSK (1.00) | CTSKCTSBCTSLCTSFCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160081937-A1 | TABLET WITH INCREASED DRUG LOAD OF ODANACATIB | HEXAL AG (DE) | 2016-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160081937-A1 | TABLET WITH INCREASED DRUG LOAD OF ODANACATIB | OSTC, SLCO1B3, SLCO1B1 | CTSK 3029/4885CTSB 956/4885CTSL 3150/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.