Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3095037 | 0.82 | HRH3 (0.60) | HRH3HRH1 | |
| SCHEMBL3094829 | 0.81 | HRH3 (0.60) | HRH3HRH1 | |
| SCHEMBL3085980 | 0.81 | HRH3 (0.64) | HRH3HRH1 | |
| SCHEMBL3081307 | 0.80 | HRH3 (0.58) | HRH3HRH1 | |
| SCHEMBL3097058 | 0.80 | NNMT (0.49) | HRH3 | |
| SCHEMBL3087639 | 0.80 | HRH3 (1.00) | HRH3HRH1 | |
| SCHEMBL1707159 | 0.80 | HRH3 (1.00) | HRH3HRH1 | |
| SCHEMBL3087219 | 0.78 | HRH3 (0.77) | HRH3HRH1 | |
| SCHEMBL14563241 | 0.76 | HRH3 (0.73) | HRH3HRH1 | |
| SCHEMBL3082047 | 0.76 | HRH3 (0.81) | HRH3HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2615090-A1 | Nitrogen-containing fused heterocyclic compounds and their use as beta amyloid production inhibitors | Eisai R&D Management Co., Ltd. (JP) | 2013-07-17 | — | — | EP | disclosed |
| EP-2424528-A2 | TREATMENT OF OSTEOARTHRITIS PAIN | Abbott Laboratories (US) | 2012-03-07 | — | — | EP | disclosed |