SCHEMBL176160

SCHEMBL176160

C=CCOC(=O)C[C@H](N)C(=O)OCC=C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.46
TSHR P16473 2/20 0.42
MAPT P10636 3/20 0.38
CACNA1B Q00975 1/20 0.38
APBA1 Q02410 1/20 0.38
CYP3A4 P08684 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
ALDH1A1 P00352 4/20 0.35
HSD17B10 Q99714 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
PKM P14618 1/20 0.35
GAA P10253 1/20 0.33
GRIK1 P39086 2/20 0.32
GRIK2 Q13002 2/20 0.32
KDM4E B2RXH2 1/20 0.32
TP53 P04637 1/20 0.32
HPGD P15428 1/20 0.32
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1023364 1.00 TDP1 (0.46) TDP1TSHRMAPTCACNA1BAPBA1
SCHEMBL2201786 0.86 GRIK1 (0.47) TDP1TSHRMAPTCACNA1BAPBA1
SCHEMBL2201794 0.86 GRIK1 (0.47) TDP1TSHRMAPTCACNA1BAPBA1
Hydrochloric Acid SCHEMBL29425835 0.85 GRIK1 (0.46) TDP1TSHRMAPTCACNA1BAPBA1
SCHEMBL6532116 0.84 MAPT (0.38) TDP1TSHRMAPTCACNA1BAPBA1
SCHEMBL2515415 0.84 MAPT (0.42) TDP1TSHRMAPTCACNA1BAPBA1
SCHEMBL1023366 0.84 MAPT (0.38) TDP1TSHRMAPTCACNA1BAPBA1
SCHEMBL10972597 0.84 MAPT (0.42) TDP1TSHRMAPTCACNA1BAPBA1
SCHEMBL22984932 0.83 SMN1; SMN2 (0.40) TDP1TSHRMAPTCACNA1BAPBA1
Hydrochloric Acid SCHEMBL8140432 0.82 MAPT (0.37) TDP1TSHRMAPTCACNA1BAPBA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2751 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101039720-A Conditioning shampoos with detergent soluble silicones COLGATE PALMOLIVE CO (US) 2007-09-19 CN claimed
EP-1799308-A1 CONDITIONING SHAMPOOS WITH DETERGENT SOLUBLE SILICONES Colgate-Palmolive Company (US) 2007-06-27 EP claimed
EP-1678289-B1 BAR SOAP COMPOSITION WITH REDUCED BAR WEAR PROPERTIES COLGATE PALMOLIVE CO (US) 2007-04-11 EP claimed
CN-1875091-A Composition with reduced bar wear COLGATE PALMOLIVE CO (US) 2006-12-06 CN claimed
EP-1678289-A1 BAR SOAP COMPOSITION WITH REDUCED BAR WEAR PROPERTIES Colgate-Palmolive Company (US) 2006-07-12 EP claimed
US-7045491-B2 Bar soap composition with reduced bar wear properties COLGATE-PALMOLIVE COMPANY (US) 2006-05-16 US claimed
WO-2006044296-A1 CONDITIONING SHAMPOOS WITH DETERGENT SOLUBLE SILICONES COLGATE-PALMOLIVE COMPANY (US) 2006-04-27 WO claimed
US-20060079415-A1 Conditioning shampoos with detergent soluble silicones COLGATE-PALMOLIVE COMPANY 2006-04-13 US claimed
US-20050107273-A1 Bar soap composition with reduced bar wear properties COLGATE-PALMOTIVE COMPANY 2005-05-19 US claimed
WO-2005044970-A1 BAR SOAP COMPOSITION WITH REDUCED BAR WEAR PROPERTIES COLGATE-PALMOLIVE COMPANY (US) 2005-05-19 WO claimed
EP-0609257-B1 METHOD OF PRODUCING IRON-ORE CONCENTRATES BY FROTH FLOTATION HENKEL KGAA (DE) 1996-06-12 EP claimed
US-12042775-B2 Consumer product comprising biodegradable delivery particles THE PROCTER & GAMBLE COMPANY (US) 2024-07-23 US disclosed
CN-118338880-A Flexible dissolvable porous sheet 宝洁公司 2024-07-12 CN disclosed
US-20240225996-A1 TREATMENT METHOD FOR TEETH AND GUMS IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) 2024-07-11 US disclosed
EP-4395732-A1 PERSONAL CARE COMPOSITIONS CONTAINING POST-BIOTIC BLENDS FOR REBALANCING SKIN MICROBIOME Colgate-Palmolive Company (US) 2024-07-10 EP disclosed
US-3988433-A PEROXY ACID BLEACH, DILUENT WAX THE PROCTER & GAMBLE COMPANY (US) 1976-10-26 US disclosed
US-3987161-A SHAMPOO THE PROCTER & GAMBLE COMPANY (US) 1976-10-19 US disclosed
US-3959462-A Hair care products containing flourocarbon polymers for keeping hair cleaner longer THE PROCTER & GAMBLE COMPANY (US) 1976-05-25 US disclosed
US-3937807-A BISBIGUANIDE COMPOUND THE PROCTER & GAMBLE COMPANY (US) 1976-02-10 US disclosed
US-3934002-A BIS-GUANIDE THE PROCTER & GAMBLE COMPANY (US) 1976-01-20 US disclosed