Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.32 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL176160 | 1.00 | TDP1 (0.46) | TDP1TSHRMAPTCACNA1BAPBA1 | |
| SCHEMBL2201786 | 0.86 | GRIK1 (0.47) | TDP1TSHRMAPTCACNA1BAPBA1 | |
| SCHEMBL2201794 | 0.86 | GRIK1 (0.47) | TDP1TSHRMAPTCACNA1BAPBA1 | |
| Hydrochloric Acid SCHEMBL29425835 | 0.85 | GRIK1 (0.46) | TDP1TSHRMAPTCACNA1BAPBA1 | |
| SCHEMBL6532116 | 0.84 | MAPT (0.38) | TDP1TSHRMAPTCACNA1BAPBA1 | |
| SCHEMBL2515415 | 0.84 | MAPT (0.42) | TDP1TSHRMAPTCACNA1BAPBA1 | |
| SCHEMBL1023366 | 0.84 | MAPT (0.38) | TDP1TSHRMAPTCACNA1BAPBA1 | |
| SCHEMBL10972597 | 0.84 | MAPT (0.42) | TDP1TSHRMAPTCACNA1BAPBA1 | |
| SCHEMBL22984932 | 0.83 | SMN1; SMN2 (0.40) | TDP1TSHRMAPTCACNA1BAPBA1 | |
| Hydrochloric Acid SCHEMBL8140432 | 0.82 | MAPT (0.37) | TDP1TSHRMAPTCACNA1BAPBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8299128-B2 | Compositions comprising polymeric micelles for drug delivery | INTEZYNE TECHNOLOGIES, INC. (US) | 2012-10-30 | — | — | US | claimed |
| US-8268936-B2 | Synthesis of hybrid block copolymers and uses thereof | INTEZYNE TECHNOLOGIES, INC. (US) | 2012-09-18 | — | — | US | claimed |
| US-8263665-B2 | Polymeric micelles for drug delivery | INTEZYNE TECHNOLOGIES, INC. (US) | 2012-09-11 | — | — | US | claimed |
| US-20120148631-A1 | PEGYLATED POLYPLEXES FOR POLYNUCLEOTIDE DELIVERY | INTEZYNE TECHNOLOGIES, INCORPORATED (US) | 2012-06-14 | — | — | US | claimed |
| US-20110124840-A1 | Synthesis of Homopolymers and Block Copolymers | INTEZYNE TECHNOLOGIES, INC. | 2011-05-26 | — | — | US | claimed |
| US-20110091534-A1 | COMPOSITIONS COMPRISING POLYMERIC MICELLES FOR DRUG DELIVERY | INTEZYNE TECHNOLOGIES, INC. (US) | 2011-04-21 | — | — | US | claimed |
| US-20110021718-A1 | SYNTHESIS OF HYBRID BLOCK COPOLYMERS AND USES THEREOF | INTEZYNE TECHNOLOGIES (US) | 2011-01-27 | — | — | US | claimed |
| US-20100159020-A1 | POLYMERIC MICELLES FOR DRUG DELIVERY | INTEZYNE TECHNOLOGIES, INC. (US) | 2010-06-24 | — | — | US | claimed |
| US-7638558-B2 | drug loaded micelle of a triblock polymer tert-butylphenylsilylpropene-polyethylene glycol-b-poly(tert-butylaspartic acid-b-polyphenylalanine-copoly( tert-buyltyrosine) has a drug-loaded inner core, a crosslinked outer core, and a hydrophilic shell | INTEZYNE TECHNOLOGIES, INC. (US) | 2009-12-29 | — | — | US | claimed |
| US-7601796-B2 | polyamideether copolymer has a hydrophilic polyethylene glycol and a hydrophobic polyamino acid blocks; modified polyethylene glycol homopolymer; forming conjugate polymer drug; resin peptides; use in pharmaceutically acceptable compositions | INTEZYNE TECHNOLOGIES, INC. (US) | 2009-10-13 | — | — | US | claimed |
| EP-1848460-A2 | SYNTHESIS OF HOMOPOLYMERS AND BLOCK COPOLYMERS | Intezyne Technologies Incorporated (US) | 2007-10-31 | — | — | EP | claimed |
| US-20070059843-A1 | Method of high-speed detection for biological analyte | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2007-03-15 | — | — | US | claimed |
| WO-2006086325-A2 | SYNTHESIS OF HOMOPOLYMERS AND BLOCK COPOLYMERS | INTEZYNE TECHNOLOGIES, INCORPORATED (US) | 2006-08-17 | — | — | WO | claimed |
| JP-10087684-A | — | — | None | — | — | JP | disclosed |
| US-20230167154-A1 | MELANOCORTIN 1 RECEPTOR LIGANDS AND METHODS OF USE | H LEE MOFFITT CANCER CT & RES (US) | 2023-06-01 | — | — | US | disclosed |
| US-11230568-B2 | Melanocortin 1 receptor ligands and methods of use | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (US) | 2022-01-25 | — | — | US | disclosed |
| WO-2000035998-A2 | ASSOCIATION OF COMPOUNDS IN CARBON DIOXIDE AND THE GELS AND/OR FOAMS FORMED THEREFROM | YALE UNIVERSITY (US) | 2000-06-22 | — | — | WO | disclosed |
| JP-H1087684-A | N-GLYCOSIDE TYPE GLYCOLIPID HAVING LONG ALKYL ASPARTATE AS HYDROPHOBIC PART | AGENCY OF IND SCIENCE & TECHNOL | 1998-04-07 | — | — | JP | disclosed |
| US-5653970-A | CLEANING COMPOUNDS; COSMETICS | LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) | 1997-08-05 | — | — | US | disclosed |
| US-5641480-A | ENHANCED STABILITY AND/OR VISCOSITY, CLARITY | LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) | 1997-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120148631-A1 | PEGYLATED POLYPLEXES FOR POLYNUCLEOTIDE DELIVERY | PARN, PUF60, PARG | TDP1 271/4885TSHR 3477/4885MAPT 2732/4885 |
| US-20110124840-A1 | Synthesis of Homopolymers and Block Copolymers | PARG, PCNA, PARN | TDP1 1461/4885TSHR 4590/4885MAPT 1435/4885 |
| US-11230568-B2 | Melanocortin 1 receptor ligands and methods of use | MC1R, MC3R, MC5R | TDP1 4446/4885TSHR 93/4885MAPT 1995/4885 |
| US-20110091534-A1 | COMPOSITIONS COMPRISING POLYMERIC MICELLES FOR DRUG DELIVERY | ABCB4, ABCB11, CLTB | TDP1 2472/4885TSHR 3728/4885MAPT 104/4885 |
| US-20230167154-A1 | MELANOCORTIN 1 RECEPTOR LIGANDS AND METHODS OF USE | MC1R, MC3R, MC5R | TDP1 4446/4885TSHR 93/4885MAPT 1995/4885 |
| US-20100159020-A1 | POLYMERIC MICELLES FOR DRUG DELIVERY | ABCB4, CLTB, CD47 | TDP1 2638/4885TSHR 3168/4885MAPT 102/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.