Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | KMO | O15229 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | PSD | A5PKW4 | 2/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17618097 | 0.97 | DHODH (0.38) | DHODHMAPTCYP19A1KDM4EMEN1 | |
| SCHEMBL17618129 | 0.96 | DHODH (0.40) | DHODHMAPTCYP19A1KDM4EMEN1 | |
| SCHEMBL19650736 | 0.95 | CYP19A1 (0.39) | DHODHMAPTKMOCYP19A1KDM4E | |
| SCHEMBL17618126 | 0.94 | KMT2A (0.35) | DHODHMAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL17369025 | 0.94 | KMT2A (0.38) | DHODHMAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL17618128 | 0.93 | KMT2A (0.36) | DHODHMAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL17618116 | 0.93 | MEN1 (0.34) | DHODHMAPTCYP19A1KDM4EMEN1 | |
| SCHEMBL17618142 | 0.92 | MEN1 (0.35) | DHODHMAPTCYP19A1CYP11B1CYP11B2 | |
| SCHEMBL17618096 | 0.91 | CYP19A1 (0.39) | DHODHMAPTCYP19A1MEN1ALDH1A1 | |
| SCHEMBL17618112 | 0.91 | MEN1 (0.34) | DHODHMAPTCYP19A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160087215-A1 | NOVEL PYRIMIDINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT DEVICES | HODOGAYA CHEMICAL CO., LTD. (JP) | 2016-03-24 | — | — | US | disclosed |
| US-20160087215-A1 | NOVEL PYRIMIDINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT DEVICES | HODOGAYA CHEMICAL CO., LTD. (JP) | 2016-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160087215-A1 | NOVEL PYRIMIDINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT DEVICES | SLC29A1, SLC29A2, DHX29 | DHODH 861/4885MAPT 3660/4885KMO 955/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.