DHX29 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL22523765	0.71	1/20
SCHEMBL3503222	0.67	1/20
SCHEMBL3503224	0.67	1/20
SCHEMBL3503226	0.53	1/20
SCHEMBL3896679	0.51	1/20
SCHEMBL3897410	0.51	1/20
SCHEMBL30089282	0.51	1/20
SCHEMBL6720997	0.47	1/20
SCHEMBL18598059	0.47	1/20
SCHEMBL14680194	0.47	1/20
SCHEMBL14680225	0.46	1/20
SCHEMBL22036585	0.42	1/20
SCHEMBL16229979	0.42	1/20
SCHEMBL14680180	0.42	1/20
SCHEMBL22036232	0.42	1/20
SCHEMBL12076	0.41	1/20

Clinical trials — most relevant to DHX29 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Long Term Extension Study in Patients With Primary Hyperoxaluria	PHASE3	ACTIVE_NOT_RECRUITING
Impact of tdrd9 Gene Mutations in the Therapeutic Response to L-carnitine in Oligoasthenozoospermic Men	PHASE3	ACTIVE_NOT_RECRUITING
Clinical Study of EBV-LMP1 Targeted DNAzyme to Treat Nasopharyngeal Carcinoma	PHASE1/PHASE2	COMPLETED
Reverse Transcriptase Inhibitors in AGS	PHASE2	COMPLETED
Pharmacogenetics of Disulfiram for Cocaine	PHASE2	COMPLETED
Whole-genome Sequencing Study in Patients With Diminished Ovarian Reserve	nan	UNKNOWN
PHF19 Gene Expression and EZH2 Gene Deletion in Acute Myeloid Leukemia	nan	UNKNOWN
Study of Individuals and Families With Aberrations in DDX41 or Similar Cancer Predisposition Variants	nan	RECRUITING
Better Delineation of DDX3X Related Phenotype and Epigenetic Signature.	nan	UNKNOWN
International PPB/DICER1 Registry	nan	RECRUITING
Genetic Analysis of Hereditary Disorders of Hearing and Balance	nan	COMPLETED
Gene Mutations and Rescue in Human Congenital Diaphragmatic Hernia	nan	UNKNOWN
Genetics of Primary Ciliary Dyskinesia	nan	COMPLETED
Speech and Short-term Memory Functions in Dyslexia: a Combined MEG and EEG Study	nan	UNKNOWN
DDX3X Syndrome -The Seaver Autism Center for Research and Treatment is Characterizing DDX3X-related Neurodevelopmental Disorders Using Genetic, Medical, and Neuropsychological Measures.	nan	COMPLETED
Prevalence of a Non-Expressing 11B Mutation in Aka Peoples of the Central African Republic	nan	COMPLETED
Genes Associated With Development of Pulmonary Arterial Hypertension in Patients With Congenital Shunt Lesions	nan	RECRUITING
Exome Analysis in Hearing Impaired Patients	nan	UNKNOWN
ADAR1 Expression Level in Rectal Cancer	nan	RECRUITING
PCD New Gene Discovery	nan	COMPLETED
Registry and Natural History Study for Early Onset Hereditary Spastic Paraplegia	nan	RECRUITING
Clinical Manifestations and Biomarkers in Amyotrophic Lateral Sclerosis Type 4 and Other Inherited Neurological Disorders of RNA Processing	nan	RECRUITING
Genetic Investigation of Cancer Predisposition	nan	NOT_YET_RECRUITING
A Proof of Concept Study for the DNA Repair Driven by the Mesenchymal Stem Cells in Critical COVID-19 Patients	nan	COMPLETED
Genetic Study of Patients With Primary Ciliary Dyskinesia	nan	COMPLETED
Phenotype/Genotype Correlations in Neuromuscular Disorders	nan	COMPLETED
Universal Rare Gene Study: A Registry and Natural History Study of Retinal Dystrophies Associated With Rare Disease-Causing Genetic Variants	nan	RECRUITING
Diaphragmatic Hernia Research & Exploration, Advancing Molecular Science	nan	RECRUITING
A Study of the Genetic Analysis of Brain Disorders	nan	COMPLETED
Congenital Hemolytic and Dyserythropoietic Anemias	nan	RECRUITING

Related proteins — ESM-2 sequence neighbours (a DHX29 binder may also engage these)

Protein	Name	Similarity
Q6PGC1	—	1.000	Q6PGC1 →
A3KMI0	—	1.000	A3KMI0 →
Q6P158	—	1.000	Q6P158 →
A3KFM7	—	1.000	A3KFM7 →
Q9C813	—	0.999	Q9C813 →
D3ZA12	—	0.999	D3ZA12 →
Q04692	—	0.999	Q04692 →
D3Z9Z9	—	0.998	D3Z9Z9 →
F4I9Q5	—	0.998	F4I9Q5 →
E1B7X9	—	0.998	E1B7X9 →
Q0D622	—	0.998	Q0D622 →
KAT8	Histone acetyltransferase KAT8	0.998	landscape →
A6QQR4	—	0.997	A6QQR4 →
Q9D3R6	—	0.997	Q9D3R6 →
KDM5B	Lysine-specific demethylase 5B	0.997	landscape →
Q9C6G0	—	0.997	Q9C6G0 →
Q19546	—	0.997	Q19546 →
Q9H1H9	—	0.997	Q9H1H9 →
Q9H4L7	—	0.997	Q9H4L7 →
Q6P5D3	—	0.997	Q6P5D3 →
Q8TD26	—	0.997	Q8TD26 →
Q05AS3	—	0.997	Q05AS3 →
Q9Y4B4	—	0.996	Q9Y4B4 →
F4IDQ6	—	0.996	F4IDQ6 →
F4IV45	—	0.996	F4IV45 →
Q5XI06	—	0.996	Q5XI06 →
Q9DF36	—	0.996	Q9DF36 →
O43150	—	0.996	O43150 →
B0R061	—	0.996	B0R061 →
B4NBP4	—	0.996	B4NBP4 →