Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.36 |
| ▸ | NPY4R | P50391 | 12/20 | 0.35 |
| ▸ | NPY1R | P25929 | 9/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 8/20 | 0.35 |
| ▸ | NPY2R | P49146 | 5/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17619962 | 0.91 | PADI4 (0.38) | PADI4 | |
| SCHEMBL17619954 | 0.91 | PADI4 (0.36) | PADI4NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL21546368 | 0.91 | PADI4 (0.36) | PADI4NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL18591492 | 0.83 | KDM4E (0.34) | KDM4EUSP2HPGDHSD17B10PADI4 | |
| SCHEMBL20791913 | 0.83 | CYP2D6 (0.38) | KDM4EUSP2HPGDHSD17B10 | |
| SCHEMBL22260620 | 0.81 | GRIN1 (0.35) | PADI4NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL17620030 | 0.81 | GRIN1 (0.35) | PADI4NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL17620029 | 0.81 | MALT1 (0.36) | PADI4NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL21546358 | 0.79 | NPY4R (0.35) | PADI4NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL22260666 | 0.78 | KDM4E (0.48) | KDM4EUSP2HPGDHSD17B10CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3194030-B1 | SUBSTITUTED PHENYLPYRROLECARBOXAMIDES WITH THERAPEUTIC ACTIVITY IN HIV | NEW YORK BLOOD CENTER INC (US) | 2019-11-06 | — | — | EP | disclosed |
| WO-2016044808-A1 | SUBSTITUTED PHENYLPYRROLECARBOXAMIDES WITH THERAPEUTIC ACTIVITY IN HIV | NEW YORK BLOOD CENTER, INC. (US) | 2016-03-24 | — | — | WO | disclosed |