Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PADI4 | Q9UM07 | 2/20 | 0.36 |
| ▸ | PADI2 | Q9Y2J8 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | NPY4R | P50391 | 7/20 | 0.33 |
| ▸ | NPY1R | P25929 | 6/20 | 0.33 |
| ▸ | NPY2R | P49146 | 3/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.33 |
| ▸ | PADI6 | Q6TGC4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17619954 | 1.00 | PADI4 (0.36) | PADI4PADI2TDP1KDM1ANPY4R | |
| SCHEMBL17619962 | 0.91 | PADI4 (0.38) | PADI4PADI2PADI6 | |
| SCHEMBL17620047 | 0.91 | KDM4E (0.39) | PADI4NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL21546358 | 0.89 | NPY4R (0.35) | PADI4PADI2NPY4RNPY1RNPY2R | |
| SCHEMBL17620029 | 0.88 | MALT1 (0.36) | PADI4PADI2TDP1KDM1ANPY4R | |
| SCHEMBL17619932 | 0.83 | SMN1; SMN2 (0.38) | — | |
| SCHEMBL17620032 | 0.83 | HRH4 (0.36) | NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL22260620 | 0.79 | GRIN1 (0.35) | PADI4PADI2NPY4RNPY1RNPY2R | |
| SCHEMBL17620030 | 0.79 | GRIN1 (0.35) | PADI4PADI2NPY4RNPY1RNPY2R | |
| SCHEMBL18591492 | 0.74 | KDM4E (0.34) | PADI4NPY4RNPY1RNPY2RNPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3194030-B1 | SUBSTITUTED PHENYLPYRROLECARBOXAMIDES WITH THERAPEUTIC ACTIVITY IN HIV | NEW YORK BLOOD CENTER INC (US) | 2019-11-06 | — | — | EP | disclosed |