Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 9/20 | 0.53 |
| ▸ | BCL2 | P10415 | 8/20 | 0.53 |
| ▸ | BID | P55957 | 1/20 | 0.53 |
| ▸ | BCL2L1 | Q07817 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 9/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17613112 | 0.91 | MEN1 (0.53) | MCL1BCL2BIDMEN1KMT2A | |
| SCHEMBL17599282 | 0.90 | MEN1 (0.55) | MCL1BCL2BIDMEN1KMT2A | |
| SCHEMBL17620396 | 0.87 | BRD1 (0.50) | MEN1KMT2AMAPTL3MBTL1HTT | |
| SCHEMBL17620399 | 0.87 | MEN1 (0.44) | MCL1BCL2BIDMEN1KMT2A | |
| SCHEMBL17620402 | 0.87 | MEN1 (0.53) | MEN1KMT2AMAPTL3MBTL1HTT | |
| SCHEMBL17613110 | 0.81 | KMT2A (0.43) | MEN1KMT2AMAPTL3MBTL1HTT | |
| SCHEMBL17613111 | 0.79 | KMT2A (0.42) | MEN1KMT2AMAPTL3MBTL1HTT | |
| SCHEMBL30064838 | 0.77 | KMT2A (0.47) | MEN1KMT2AMAPTL3MBTL1HTT | |
| SCHEMBL22228999 | 0.77 | KMT2A (0.47) | MEN1KMT2AMAPTL3MBTL1HTT | |
| SCHEMBL17620395 | 0.75 | MEN1 (0.54) | MCL1BCL2BIDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3182203-A1 | A COMBINATION OF NIT DERIVATIVES WITH SENSITIZERS | Heraeus Precious Metals North America Daychem LLC (US) | 2017-06-21 | — | — | EP | disclosed |
| WO-2016043558-A1 | PHOTO-ACID GENERATING AGENT | HERAEUS MATERIALS KOREA CORPORATION (KR) | 2016-03-24 | — | — | WO | disclosed |