⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7755979 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL8420349 | 0.69 | — | — | |
| SCHEMBL1662549 | 0.67 | — | — | |
| SCHEMBL13975634 | 0.67 | — | — | |
| SCHEMBL15923452 | 0.67 | — | — | |
| SCHEMBL31501143 | 0.67 | — | — | |
| SCHEMBL1036977 | 0.67 | — | — | |
| SCHEMBL15924313 | 0.67 | — | — | |
| SCHEMBL6307099 | 0.67 | — | — | |
| Bromide SCHEMBL2387784 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 114 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112823151-B | Compounds and compositions for the treatment of diseases associated with STING activity | 艾福姆德尤股份有限公司 | 2024-11-15 | — | — | CN | disclosed |
| US-20210236466-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | NOVARTIS PHARMA AG (CH) | 2021-08-05 | — | — | US | disclosed |
| US-20210236466-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | NOVARTIS PHARMA AG (CH) | 2021-08-05 | — | — | US | disclosed |
| CN-112823151-A | Compounds and compositions for treating diseases associated with STING activity | 艾福姆德尤股份有限公司 | 2021-05-18 | — | — | CN | disclosed |
| EP-3818044-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM Due, Inc. (US) | 2021-05-12 | — | — | EP | disclosed |
| CN-108191944-B | Sesquiterpenes aspertepinol B derivative from marine microorganisms, synthetic method and carbohydrase application | 华南师范大学 | 2020-12-11 | — | — | CN | disclosed |
| CN-108299541-B | Sesquiterpenes aspertepinol B derivative from marine microorganisms, synthetic method and anti-inflammatory application | 华南师范大学 | 2020-12-11 | — | — | CN | disclosed |
| WO-2020150417-A2 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM DUE, INC. (US) | 2020-07-23 | — | — | WO | disclosed |
| WO-2020150417-A2 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM DUE, INC. (US) | 2020-07-23 | — | — | WO | disclosed |
| CN-110526921-A | A kind of compound and its preparation method and application with anti-inflammatory effect | WEST CHINA HOSPITAL SICHUAN UNIV | 2019-12-03 | — | — | CN | disclosed |
| US-20150111938-A1 | PROCESSES FOR THE PREPARATION OF PESTICIDAL COMPOUNDS | DOW AGROSCIENCES LLC | 2015-04-23 | — | — | US | disclosed |
| US-8937064-B2 | Pyrazolo[1,5-a]pyrimidines useful as JAK2 inhibitors | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2015-01-20 | — | — | US | disclosed |
| CN-103917545-A | BTK inhibitors | MERCK SHARP & DOHME | 2014-07-09 | — | — | CN | disclosed |
| CN-103619171-A | Pesticidal compositions and methods related thereto | DOW AGROSCIENCES LLC | 2014-03-05 | — | — | CN | disclosed |
| US-20110118255-A1 | PYRAZOLO[1,5-a]PYRIMIDINES USEFUL AS JAK2 INHIBITORS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2011-05-19 | — | — | US | disclosed |
| CN-101932583-A | Pyrazolo [1,5-a] pyrimidines useful as jak2 inhibitors | VERTEX PHARMA | 2010-12-29 | — | — | CN | disclosed |
| EP-2252618-A1 | PYRAZOLO [1,5-a] PYRIMIDINES USEFUL AS JAK2 INHIBITORS | Vertex Pharmaceuticals Incorporated (US) | 2010-11-24 | — | — | EP | disclosed |
| WO-2009085913-A1 | PYRAZOLO [1,5-a] PYRIMIDINES USEFUL AS JAK2 INHIBITORS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2009-07-09 | — | — | WO | disclosed |
| US-7435831-B2 | Bicyclic and bridged nitrogen heterocycles | CHEMOCENTRYX, INC. (US) | 2008-10-14 | — | — | US | disclosed |
| US-7435830-B2 | Bicyclic and bridged nitrogen heterocycles | CHEMOCENTRYX, INC. (US) | 2008-10-14 | — | — | US | disclosed |