SCHEMBL1662549

SCHEMBL1662549

Nc1c[nH]nc1Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL2692202 0.97
Hydrochloric Acid SCHEMBL8420349 0.69
SCHEMBL31501143 0.67
SCHEMBL21737049 0.67
SCHEMBL1762079 0.67
SCHEMBL5813411 0.67
SCHEMBL9280097 0.67
SCHEMBL6307099 0.67
SCHEMBL13975634 0.67
SCHEMBL22425324 0.66 ALDH1A1 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 274 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116947813-A Preparation method of 3-chloro-4-amino-1- (3-pyridyl) -1H-pyrazole 绍兴贝斯美化工股份有限公司 2023-10-27 CN claimed
CN-110325036-B Process for preparing pesticidal compounds 美国陶氏益农公司 2021-10-26 CN claimed
CN-110325036-A Process for preparing pesticidal compounds 美国陶氏益农公司 2019-10-11 CN claimed
US-10233155-B2 Processes for the preparation of pesticide compounds DOW AGROSCIENCES LLC (US) 2019-03-19 US claimed
CN-105636445-B Process for preparing pesticidal compounds 美国陶氏益农公司 2018-12-07 CN claimed
EP-3057427-B1 PROCESSES FOR THE PREPARATION OF PESTICIDAL COMPOUNDS DOW AGROSCIENCES LLC (US) 2018-07-18 EP claimed
CN-105636446-B The method for preparing Pesticidal compound 美国陶氏益农公司 2018-07-13 CN claimed
US-20180186750-A1 PROCESSES FOR THE PREPARATION OF PESTICIDE COMPOUNDS CORTEVA AGRISCIENCE LLC 2018-07-05 US claimed
WO-2018125817-A1 PROCESSES FOR THE PREPARATION OF PESTICIDAL COMPOUNDS DOW AGROSCIENCES LLC (US) 2018-07-05 WO claimed
CN-105636444-B Process for preparing pesticidal compounds 美国陶氏益农公司 2018-04-27 CN claimed
CN-105636442-A Processes for the preparation of pesticidal compounds DOW AGROSCIENCES LLC 2016-06-01 CN claimed
CN-105636444-A Process for preparing pesticidal compounds DOW AGROSCIENCES LLC 2016-06-01 CN claimed
WO-2015058024-A1 PROCESSES FOR THE PREPARATION OF PESTICIDAL COMPOUNDS DOW AGROSCIENCES LLC (US) 2015-04-23 WO claimed
CN-101039946-B Disubstituted pyrazolobenzodiazepines useful as inhibitors for CDK2 and angiogenesis and for the treatment of breast, colon, lung and prostate cancer HOFFMANN LA ROCHE 2010-12-08 CN claimed
US-7524840-B2 7,8-disubstituted pyrazolobenzodiazepines HOFFMANN-LA ROCHE INC. (US) 2009-04-28 US claimed
EP-1802625-B1 DISUBSTITUTED PYRAZOLOBENZODIAZEPINES USEFUL AS INHIBITORS FOR CDK2 AND ANGIOGESIS, AND FOR THE TREATMENT OF BREAST, COLON, LUNG AND PROSTATE CANCER HOFFMANN LA ROCHE (CH) 2008-06-18 EP claimed
CN-101039946-A Disubstituted pyrazolobenzodiazepines * useful as inhibitors for CDK2 and angiogenesis and for the treatment of breast, colon, lung and prostate cancer HOFFMANN LA ROCHE (CH) 2007-09-19 CN claimed
EP-1802625-A1 DISUBSTITUTED PYRAZOLOBENZODIAZEPINES USEFUL AS INHIBITORS FOR CDK2 AND ANGIOGESIS, AND FOR THE TREATMENT OF BREAST, COLON, LUNG AND PROSTATE CANCER F. Hoffmann-Roche AG (CH) 2007-07-04 EP claimed
WO-2006040036-A1 DISUBSTITUTED PYRAZOLOBENZODIAZEPINES USEFUL AS INHIBITORS FOR CDK2 AND ANGIOGESIS, AND FOR THE TREATMENT OF BREAST, COLON, LUNG AND PROSTATE CANCER F. HOFFMANN-LA ROCHE AG (CH) 2006-04-20 WO claimed
US-20060079511-A1 7,8-Disubstituted pyrazolobenzodiazepines LIU JIN-JUN 2006-04-13 US claimed